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Histone Methylation

Histone methylation causes transcription repression or activation, depending on the target sites. Histone methyltransferases (HMTs) control or regulate DNA methylation through chromatin-dependent transcription repression or activation. Measurement of histone methyltrasferase activity and quantification of histone methylation patterns have become pivotal in studying epigenetic regulation of genes, as well as inhibitor discovery.

Histone Methylation Quantification

Histone methylation is a reversible process by which methyl groups are covalently added to histones. It plays a critical role in regulating gene expression, as it can alter the accessibility of DNA to the cellular machinery that reads and interprets it. Types of Histone Methylation There are several different types of histone methylation, including: Lysine Methylation Lysine methylation can occur at various positions on the hist...

Histone Methyltransferase Assay

Histone methyltransferases (HMTs) are enzymes that catalyze the transfer of methyl groups to histones. Methylation of histones can regulate the accessibility of DNA to the cellular machinery that reads and interprets the genetic code. Such epigenetic regulation can influence a wide range of cellular processes, including gene expression, DNA repair, and DNA replication. There are several different types of HMTs that can methylate different amino acid residues on histo...

Histone Demethylase Assay

Histone demethylases are enzymes that remove methyl groups from histones. The addition or removal of methyl groups to histones can affect the way that DNA is packaged and, in turn, can regulate gene expression. The discovery of histone demethylases demonstrated that histone methylation is not a permanent modification, but rather a more dynamic process. Role in Biological Processes and Disease Treatment Measuring the activity and inhibition of histone demethylases ...

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EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K4)

Citations (21)

Input Type:	Nuclear Extracts, Purified Enzyme
Research Area:	Histone Methylation
Target Application:	Activity Measurement
Vessel Format:	96-Well Plate

P-3002-1	48 assays	$398.00
P-3002-2	96 assays	$659.00

Research Kits

EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K9)

Citations (32)

Input Type:	Nuclear Extracts, Purified Enzyme
Research Area:	Histone Methylation
Target Application:	Activity Measurement
Vessel Format:	96-Well Plate

P-3003-1	48 assays	$398.00
P-3003-2	96 assays	$659.00

Research Kits

EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K27)

Citations (29)

Input Type:	Nuclear Extracts, Purified Enzyme
Research Area:	Histone Methylation
Target Application:	Activity Measurement
Vessel Format:	96-Well Plate

P-3005-48	48 assays	$398.00
P-3005-96	96 assays	$659.00

Research Kits

EpiQuik In Situ Histone H3K27 Tri-Methylation Assay Kit

Input Type:	Cells
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3014T-096	96 assays	$458.00
P-3014T-192	2x96 assays	$780.00

Research Kits

EpiQuik In Situ Histone H3K4 Methylation Assay Kit

Citations (1)

Input Type:	Cells
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3015-096	96 assays	$458.00
P-3015-192	2x96 assays	$780.00

Research Kits

EpiQuik In Situ Histone H3K9 Methylation Assay Kit

Input Type:	Cells
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3016-096	96 assays	$458.00
P-3016-192	2x96 assays	$780.00

Research Kits

EpiQuik Global Histone H3K4 Methylation Assay Kit

Citations (16) | (1)

Input Type:	Cells, Unisolated Samples
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3017-48	48 assays	$434.00
P-3017-96	96 assays	$646.00

Research Kits

EpiQuik Global Histone H3K9 Methylation Assay Kit

Citations (18)

Input Type:	Cells, Unisolated Samples
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3018-48	48 assays	$434.00
P-3018-96	96 assays	$646.00

Research Kits

EpiQuik Global Histone H3K27 Methylation Assay Kit

Citations (12) | (2)

Input Type:	Cells, Unisolated Samples
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3020-48	48 assays	$434.00
P-3020-96	96 assays	$646.00

Research Kits

EpiQuik Global Histone H3K27 Tri-Methylation Assay Kit

Citations (1)

Input Type:	Cells, Unisolated Samples
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3020T-48	48 assays	$434.00
P-3020T-96	96 assays	$646.00

Research Kits

EpiQuik Global Di-Methyl Histone H3K4 Quantification Kit (Colorimetric)

Citations (4)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3022-48	48 assays	$303.00
P-3022-96	96 assays	$569.00

Research Kits

EpiQuik Global Di-Methyl Histone H3K4 Quantification Kit (Fluorometric)

Citations (1)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3023-48	48 assays	$303.00
P-3023-96	96 assays	$569.00

Research Kits

EpiQuik Global Mono-Methyl Histone H3K4 Quantification Kit (Colorimetric)

Citations (2)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3024-48	48 assays	$303.00
P-3024-96	96 assays	$569.00

Research Kits

EpiQuik Global Mono-Methyl Histone H3K4 Quantification Kit (Fluorometric)

Citations (1)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3025-48	48 assays	$303.00
P-3025-96	96 assays	$569.00

Research Kits

EpiQuik Global Tri-Methyl Histone H3K4 Quantification Kit (Colorimetric)

Citations (12)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3026-48	48 assays	$303.00
P-3026-96	96 assays	$569.00

Research Kits

EpiQuik Global Tri-Methyl Histone H3K4 Quantification Kit (Fluorometric)

Citations (2)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3027-48	48 assays	$303.00
P-3027-96	96 assays	$569.00

Research Kits

EpiQuik Global Pan-Methyl Histone H3K4 Quantification Kit (Colorimetric)

Citations (6)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3028-96

96 assays

$569.00

Research Kits

EpiQuik Global Pan-Methyl Histone H3K4 Quantification Kit (Fluorometric)

Citations (3)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3029-96

96 assays

$569.00

Research Kits

EpiQuik Global Mono-Methyl Histone H3K9 Quantification Kit (Colorimetric)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3030-48	48 assays	$303.00
P-3030-96	96 assays	$569.00

Research Kits

EpiQuik Global Mono-Methyl Histone H3K9 Quantification Kit (Fluorometric)

Citations (1)

Input Type:	Histone Extracts
Research Area:	Histone Methylation
Target Application:	Amount Quantitation
Vessel Format:	96-Well Plate

P-3031-48	48 assays	$303.00
P-3031-96	96 assays	$569.00

Research Kits

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Displaying 1 to 20 (of 95 products)

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