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Phosphatase Antibodies

Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Two important phosphatases include the serine/threonine protein phosphatase 2A (PP2A) and phosphatase and tensin homolog (PTEN). PP2A is a key phosphatase as it catalyzes dephosphorylation of many proteins, but also dephosphorylates the main protein kinases responsible for activation of major signaling pathways, including AKT, ERK MAP kinase and Protein kinase C (PKC) family members. PTEN dephosphorylates proteins, as well as the phospholipid phosphatidylinositol (3,4,5)-trisphosphate (PIP3), which induces inhibition of signaling by AKT, a critical pathway involved in cellular growth and proliferation. PTEN is a tumor suppressor frequently mutated and involved in the pathogenesis and progression of several cancers.
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Image Description Cat. No. Size Price
CTDNEP1 Polyclonal Antibody
CTDNEP1 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A54013-05050 µg $249.00 Add to Cart
A54013-100100 µg $349.00 Add to Cart
Antibodies
CTDNEP1 Polyclonal Antibody, Biotin Conjugated
CTDNEP1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A54016-05050 µg $249.00 Add to Cart
A54016-100100 µg $349.00 Add to Cart
Antibodies
CTDNEP1 Polyclonal Antibody, FITC Conjugated
CTDNEP1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A54015-05050 µg $249.00 Add to Cart
A54015-100100 µg $349.00 Add to Cart
Antibodies
CTDNEP1 Polyclonal Antibody, HRP Conjugated
CTDNEP1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A54014-05050 µg $249.00 Add to Cart
A54014-100100 µg $349.00 Add to Cart
Antibodies
DUSP1 Monoclonal Antibody [4H7]
DUSP1 Monoclonal Antibody [4H7]

Application: ELISA, WB
Areas of Research: Signal Transduction
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG1 Kappa
Purification: Affinity Purified
Reactivity: Human
A-7174-100100 µg $452.00 Add to Cart
Antibodies
DUSP13 Polyclonal Antibody
DUSP13 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A55339-05050 µg $249.00 Add to Cart
A55339-100100 µg $349.00 Add to Cart
Antibodies
DUSP13 Polyclonal Antibody, Biotin Conjugated
DUSP13 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A55342-05050 µg $249.00 Add to Cart
A55342-100100 µg $349.00 Add to Cart
Antibodies
DUSP13 Polyclonal Antibody, FITC Conjugated
DUSP13 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A55341-05050 µg $249.00 Add to Cart
A55341-100100 µg $349.00 Add to Cart
Antibodies
DUSP13 Polyclonal Antibody, HRP Conjugated
DUSP13 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A55340-05050 µg $249.00 Add to Cart
A55340-100100 µg $349.00 Add to Cart
Antibodies
DUSP19 Polyclonal Antibody
DUSP19 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67062-05050 µg $249.00 Add to Cart
A67062-100100 µg $349.00 Add to Cart
Antibodies
DUSP19 Polyclonal Antibody, Biotin Conjugated
DUSP19 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67065-05050 µg $249.00 Add to Cart
A67065-100100 µg $349.00 Add to Cart
Antibodies
DUSP19 Polyclonal Antibody, FITC Conjugated
DUSP19 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67064-05050 µg $249.00 Add to Cart
A67064-100100 µg $349.00 Add to Cart
Antibodies
DUSP19 Polyclonal Antibody, HRP Conjugated
DUSP19 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67063-05050 µg $249.00 Add to Cart
A67063-100100 µg $349.00 Add to Cart
Antibodies
DUSP21 Polyclonal Antibody
DUSP21 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67570-05050 µg $249.00 Add to Cart
A67570-100100 µg $349.00 Add to Cart
Antibodies
DUSP21 Polyclonal Antibody, Biotin Conjugated
DUSP21 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67573-05050 µg $249.00 Add to Cart
A67573-100100 µg $349.00 Add to Cart
Antibodies
DUSP21 Polyclonal Antibody, FITC Conjugated
DUSP21 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67572-05050 µg $249.00 Add to Cart
A67572-100100 µg $349.00 Add to Cart
Antibodies
DUSP21 Polyclonal Antibody, HRP Conjugated
DUSP21 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67571-05050 µg $249.00 Add to Cart
A67571-100100 µg $349.00 Add to Cart
Antibodies
DUSP26 Polyclonal Antibody
DUSP26 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human, Mouse
A51241-05050 µg $249.00 Add to Cart
A51241-100100 µg $349.00 Add to Cart
Antibodies
DUSP26 Polyclonal Antibody, Biotin Conjugated
DUSP26 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A51244-05050 µg $249.00 Add to Cart
A51244-100100 µg $349.00 Add to Cart
Antibodies
DUSP26 Polyclonal Antibody, FITC Conjugated
DUSP26 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A51243-05050 µg $249.00 Add to Cart
A51243-100100 µg $349.00 Add to Cart
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 164 products)
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