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Primary Antibodies

Primary Antibodies

Primary antibodies are reagents that bind directly to a specific target antigen of interest. They are useful for investigating biomarkers for diseases including cancer, Alzheimer’s, and Parkinson’s. Primary antibodies can directly bind to specific antigens such as peptides, proteins, or other molecules. Various modifications such as DNA methylation, histone acetylation, and phosphorylation can also be studied by using primary antibodies.
DNA Methylation Antibodies
Epigentek's well characterized and highly validated DNA methylation antibodies and DNA demethylation antibodies may help to increase researchers' understanding of DNA methylation and its involvement in diseases as well as cell cycle regulation and embryonic development. DNA methylation is the most widely studied epigenetic mechanism that regulates gene expression, thereby affecting cell function, while aberrant DNA methylation is prevalent in many diseases, particularly cancer.

Histone Modification Antibodies
Histone modification antibodies are used to investigate epigenetic modifications to histones such as acetylation, methylation, and phosphorylation. Histone methylation is associated with transcriptional repression or activation via the transfer of methyl groups to lysine or arginine residues of histone proteins and is crucial to studying epigenetic gene regulation with the use of histone methylation antibodies. Histone methyltransferases (HMTs) are responsible for catalyzing this proce...

RNA Processing & Modification Antibodies
RNA processing and modifications to RNA are crucial to numerous cell functions and give insight into a multitude of biological processes that are influenced by RNA activities, such as RNA interference. RNA interference (RNAi) is a gene-regulating process in which genes are silenced by RNA molecules such as shRNA, siRNA, and miRNA, usually destroying mRNA molecules and lowering protein expression. RNAi and gene silencing antibodies target the proteins involved in the various steps of g...

Chromatin & Transcription Antibodies
Antibodies that target proteins associated with chromatin and transcription such as histone deacetylases (HDACs), histone acetyltransferases (HATs), histone methyltransferases (HMTs), and HP1 are important to understanding the epigenetic regulation of chromatin structure and its function. Chromatin is involved in crucial functions of the cell including division, replication, and gene expression.

Cell Structure & Function Antibodies
Cell structure & function antibodies are used for investigating cell structure and function and include those linked to DNA damage & repair, cell cycle, apoptosis, cellular structure, and trafficking. Cell structure and function antibodies can be used to connect structural features of the cell, such as the cytoskeleton, including microtubules and microfilament, to their function. Cell cycle antibodies are targeted against proteins involved in the steps of the cell cycle, including the ...

Signal Transduction Antibodies
Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intrac...

Metabolism Antibodies
Metabolism is the chemical process catalyzed by certain enzymes by which organisms convert various substances to energy in order to sustain life. Metabolism antibodies are crucial for studying glucose, lipid, protein and nucleotide metabolism. It can be broken into two categories: catabolism and anabolism. Cellular respiration, for example, is a catabolic process as it breaks down substances. Building up nucleic acids and proteins, on the other hand, is anabolic. Understanding metaboli...

Immunology & Inflammation Antibodies
Immunology and inflammation antibodies include cell marker and receptor antibodies, cytokine antibodies, and others. Epigenetic mechanisms have been closely involved in inflammatory pathways and using antibodies that recognize specific antigens related to the immune system and inflammation offers researchers insight into the potential pathological epigenetic modifications and immunological and inflammatory complications linked to a multitude of diseases.

Other Primary Antibodies
Antibodies used for various applications, including the recently discovered gene editing and genetic engineering system known as the CRISPR/Cas9 system. The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and Cas9 (CRISPR associated system or CRISPR associated protein 9 nuclease) system delivers RNA-guided nuclease (Cas9) and specific guide RNAs (gRNA) into a cell.

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Image Description Cat. No. Size Price
12(L)-HETE Polyclonal Antibody
12(L)-HETE Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Metabolism, Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Purification: Serum
Reactivity: Species Independent
A-0406-100100 µl $399.00 Add to Cart
Antibodies
14-3-3 (pSer185) Polyclonal Antibody
14-3-3 (pSer185) Polyclonal Antibody

Application: WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Sheep
Purification: Affinity Purified
Reactivity: Cow, Human, Mouse, Rat, Sheep
A-7443-02525 µl $143.00 Discontinued
A-7443-100100 µl $499.00 Add to Cart
Antibodies
14-3-3 Beta/Epsilon/Zeta Monoclonal Antibody [3C8]
14-3-3 Beta/Epsilon/Zeta Monoclonal Antibody [3C8]

Application: WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG2b
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
A-0459-100100 µg $431.00 Add to Cart
Antibodies
14-3-3 Beta/Zeta Monoclonal Antibody [2IID8B]
14-3-3 Beta/Zeta Monoclonal Antibody [2IID8B]

Application: ICC, IHC, WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG
Purification: Affinity Purified
Reactivity: Bovine, Dog, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
A-0458-02525 µg $153.00 Discontinued
A-0458-100100 µg $380.00 Add to Cart
Antibodies
14-3-3 Epsilon (NT) Polyclonal Antibody
14-3-3 Epsilon (NT) Polyclonal Antibody

Application: AFC, ELISA, IHC, WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Purification: Serum
Reactivity: Chicken, Cow, Human, Mouse, Rat, Sheep
A-0653-02525 µl $143.00 Discontinued
A-0653-100100 µl $499.00 Add to Cart
Antibodies
14-3-3 Eta Polyclonal Antibody
14-3-3 Eta Polyclonal Antibody

Application: IHC, WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Purification: Serum
Reactivity: Chicken, Cow, Human, Mouse, Rat, Sheep
A-0651-100100 µl $499.00 Add to Cart
Antibodies
14-3-3 Gamma Polyclonal Antibody
14-3-3 Gamma Polyclonal Antibody

Application: AFC, ELISA, IHC, WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Purification: Serum
Reactivity: Chicken, Cow, Human, Mouse, Rat, Sheep
A-0652-02525 µl $143.00 Discontinued
A-0652-100100 µl $534.00 Add to Cart
Antibodies
14-3-3 Polyclonal Antibody
14-3-3 Polyclonal Antibody

Application: IHC, IP, WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Purification: Serum
Reactivity: Chicken
A-0655-02525 µl $143.00 Discontinued
A-0655-100100 µl $534.00 Add to Cart
Antibodies
14-3-3 Zeta Polyclonal Antibody
14-3-3 Zeta Polyclonal Antibody

Application: AFC, ELISA, IHC, WB
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Purification: Serum
Reactivity: Chicken, Cow, Human, Mouse, Rat, Sheep
A-0654-02525 µl $143.00 Discontinued
A-0654-100100 µl $499.00 Add to Cart
Antibodies
19S Proteasome (ADRM1) Polyclonal Antibody
19S Proteasome (ADRM1) Polyclonal Antibody

Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
A-8505-02525 µl $143.00 Discontinued
A-8505-100100 µl $452.00 Discontinued
Antibodies
5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody [HMC/4D9]
5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody [HMC/4D9]

Citations (4)
Application: DB, ELISA, IF, IHC, MeDIP
Areas of Research: DNA Methylation
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG1
Purification: Affinity Purified
Reactivity: Broad Range
A-1018-01010 µg $69.00 Add to Cart
A-1018-05050 µg $194.00 Add to Cart
A-1018-100100 µg $359.00 Add to Cart
Antibodies
5-Hydroxymethyluridine Polyclonal Antibody
5-Hydroxymethyluridine Polyclonal Antibody

Application: ELISA
Areas of Research: RNA Processing and Modification
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Goat
Isotype: IgG
Purification: Serum
Reactivity: Human
A-1300-10.1 ml $399.00 Add to Cart
Antibodies
5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]
5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]

Citations (62) | (2)
Application: DB, ELISA, IF, IHC, IP, MeDIP
Areas of Research: DNA Methylation
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG1
Purification: Affinity Purified
Reactivity: Broad Range
A-1014-01010 µg $69.00 Add to Cart
A-1014-05050 µg $199.00 Add to Cart
A-1014-100100 µg $369.00 Add to Cart
Antibodies
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody

Application: ELISA, IH
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Goat
Isotype: IgG
Purification: Serum
Reactivity: Broad Range
A-6300-10.1 ml $421.00 Add to Cart
Antibodies
8-iso-PGF2alpha Polyclonal Antibody
8-iso-PGF2alpha Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Metabolism, Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Serum
Reactivity: Species Independent
A-0403-100100 µl $328.00 Add to Cart
Antibodies
A20 Monoclonal Antibody [8E8.38]
A20 Monoclonal Antibody [8E8.38]

Areas of Research: Cell Cycle
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG1
A-0536-05050 µg $462.00 Discontinued
Antibodies
A4GNT Polyclonal Antibody
A4GNT Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62026-05050 µg $249.00 Add to Cart
A62026-100100 µg $349.00 Add to Cart
Antibodies
A4GNT Polyclonal Antibody, Biotin Conjugated
A4GNT Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62029-05050 µg $249.00 Add to Cart
A62029-100100 µg $349.00 Add to Cart
Antibodies
A4GNT Polyclonal Antibody, FITC Conjugated
A4GNT Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62028-05050 µg $249.00 Add to Cart
A62028-100100 µg $349.00 Add to Cart
Antibodies
A4GNT Polyclonal Antibody, HRP Conjugated
A4GNT Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62027-05050 µg $249.00 Add to Cart
A62027-100100 µg $349.00 Add to Cart
Antibodies
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