LoadingLoading
  • Browse By Category

  • Products
  • Services
  • Support
  • Corporate
  • Back
  • Products

  • Antibodies
  • Instruments
  • Research Kits
  • Proteins & Enzymes
  • Peptides
  • COVID-19 Assays
  • Back
  • Antibodies

  • Primary Antibodies
  • Secondary Antibodies
  • Tag Antibodies
  • Antibody Panel Packs
  • Back
  • Primary Antibodies

  • DNA Methylation Antibodies
  • Cell Structure & Function Antibodies
  • RNA Processing & Modification Antibodies
  • Chromatin & Transcription Antibodies
  • Other Primary Antibodies
  • Histone Modification Antibodies
  • Signal Transduction Antibodies
  • Metabolism Antibodies
  • Immunology & Inflammation Antibodies
  • Back
  • Cell Structure & Function Antibodies

  • DNA Damage & Repair Antibodies
  • Apoptosis & Cell Death Antibodies
  • Cell Cycle Antibodies
  • Cellular Structure Antibodies
  • Trafficking Antibodies
  • Back
  • Chromatin & Transcription Antibodies

  • DNA Replication & Transcription Antibodies
  • Chromatin Remodeling Antibodies
  • Cell Growth Antibodies
  • Development & Differentiation Antibodies
  • Back
  • Histone Modification Antibodies

  • Histone Methylation (Lysine) Antibodies
  • Histone Acetylation Antibodies
  • Histone Phosphorylation Antibodies
  • Ubiquitination & SUMOylation Antibodies
  • Histone Methylation (Arginine) Antibodies
  • Other Histone Methylation Antibodies
  • Other Histone Acetylation Antibodies
  • Histone Deacetylation Antibodies
  • Other Histone Antibodies
  • Back
  • Signal Transduction Antibodies

  • Cell Surface Receptor & Kinase Antibodies
  • Intracellular Kinase & Adaptor Protein Antibodies
  • Phosphatase Antibodies
  • Secreted Growth Factor Antibodies
  • Back
  • Metabolism Antibodies

  • Glucose Metabolism Antibodies
  • Lipid Metabolism Antibodies
  • Protein Metabolism Antibodies
  • Nucleotide Metabolism Antibodies
  • Back
  • Immunology & Inflammation Antibodies

  • Cell Marker & Receptor Antibodies
  • Cytokine Antibodies
  • Other Immunology Antibodies
  • Back
  • Antibody Panel Packs

  • Histone Modification
  • DNA Methylation
  • Back
  • Instruments

  • Sonication Devices
  • Magnets & Sample Mixers
  • Back
  • Research Kits

  • DNA Methylation
  • Chromatin & Transcription
  • Histone Methylation
  • Acetylation & Deacetylation
  • Gene Editing & Silencing
  • Sample Preparation
  • DNA Damage & Repair
  • Next Generation Sequencing
  • RNA Methylation
  • Other Histone Modifications
  • Back
  • DNA Methylation

  • DNA Bisulfite Conversion
  • DNA Methylation Quantification
  • DNA Methyltransferase & Demethylase Assays
  • Methylated DNA Immunoprecipitation
  • Methylated DNA Amplification
  • Back
  • Chromatin & Transcription

  • General Chromatin Immunoprecipitation
  • In Vitro Protein-DNA Interaction
  • Methyl-Histone Chromatin IP
  • Acetyl-Histone Chromatin IP
  • Methyl-DNA Binding Protein ChIP
  • Chromatin Analysis
  • Back
  • Histone Methylation

  • Histone Methyltransferase Assay
  • Histone Methylation Quantification
  • Histone Demethylase Assay
  • Back
  • Acetylation & Deacetylation

  • Histone Acetyltransferase (HAT) Assay
  • Histone Deacetylase (HDAC) Assay
  • Histone Acetylation Quantification
  • Back
  • Sample Preparation

  • DNA Preparation
  • Protein Preparation
  • Chromatin Preparation
  • RNA Preparation
  • Back
  • Other Histone Modifications

  • Sumoylation
  • Histone Phosphorylation Assay
  • Histone Citrullination
  • Back
  • Proteins & Enzymes

  • DNA Methylation/Demethylation Proteins
  • Methylated DNA Binding Proteins
  • Unmodified Histone Proteins
  • Chromatin Binding/Transcription Proteins
  • ADP Ribose Proteins
  • DNA Damage & Repair Proteins
  • Modified Histone Proteins
  • Back
  • DNA Methylation/Demethylation Proteins

  • DNA Demethylation Proteins
  • DNA Methylation Proteins
  • Back
  • Modified Histone Proteins

  • Histone Methylation Proteins
  • Histone Demethylation Proteins
  • Histone Acetylation Proteins
  • Histone Deacetylation Proteins
  • Histone Phosphorylation Proteins
  • Histone Sumoylation Proteins
  • Back
  • Peptides

  • Histone Methylation Peptides
  • Histone Acetylation Peptides
  • Histone Phosphorylation Peptides
  • Back
  • COVID-19 Assays

  • COVID-19 Kits
  • COVID-19 Antibodies
  • COVID-19 Proteins
  • Back
  • Services

  • DNA-based NGS Services
  • Chromatin-based NGS Services
  • qPCR-based Services
  • ELISA-based Services
  • Back
  • DNA-based NGS Services

  • Reduced Representation Bisulfite Sequencing (RRBS)
  • Whole Genome Bisulfite Sequencing (WGBS)
  • Targeted Bisulfite Sequencing
  • Back
  • Chromatin-based NGS Services

  • ChIP Sequencing (Histone Modifications)
  • Back
  • qPCR-based Services

  • Methylation-Specific qPCR (MSP)
  • Back
  • ELISA-based Services

  • Global DNA 5-mC Quantification
  • Global DNA 5-hmC Quantification
  • Global RNA 5-mC Quantification
  • Global RNA m6A Quantification
  • Histone Modification Quantification
  • Back
  • Support

  • Technical Support
  • Quality Assurance
  • Resources
  • Back
  • Technical Support

  • Submit Support Ticket
  • Back
  • Quality Assurance

  • Epigentek Gurantee
  • Risk-Free Testing: Pioneer Program
  • Product Review Program
  • Back
  • Resources

  • Epigenetics Newsletter
  • Intro to Epigenetics
  • What is Epigenetics?
  • Back
  • Corporate

  • Company Information
  • Procurement
  • Communication
  • Back
  • Company Information

  • About Epigentek
  • Press Release
  • Career Opportunities
  • Back
  • Procurement

  • Ordering Information
  • New Lab Startup Program
  • Distributors & Resellers
  • Back
  • Communication

  • Contact Us
  • Customer Feedback Survey
  • Events Calendar
Epigentek Home
Cart (0)
Datasheet
Track
Account
  • Products

    Research Kits

    • DNA Methylation
      • Global DNA Methylation Quantification
      • DNA Bisulfite Conversion
      • Methylated DNA Immunoprecipitation
      • DNMT & DNA Demethylase Assay
      • Methylated DNA Amplification
    • RNA Methylation
      • Global RNA Methylation Quantification
      • Transcriptome-Specific RNA Methylation
      • RNA Methylation Activity/Inhibition
    • Chromatin & Transcription
      • Chromatin Immunoprecipitation
      • CUT&RUN-Fast and more
      • Chromatin Accessibility
      • In Vitro Protein-DNA Interaction
    • Histone Modification
      • Histone Methylation Quantification
      • Histone Methytransferase (HMT) Assay
      • Histone Demethylase (KDM) Assay
      • Histone Acetylation Quantification
      • Histone Acetylase (HAT) Assay
      • Histone Deacetylase (HDAC) Assay
      • Histone Citrullination
      • Histone Phosphorylation
      • Histone SUMOylation
    • Protein-RNA Interaction
    • DNA/RNA Damage & Repair
    • Gene Editing & Silencing
      • Oxidative Cell Damage
      • Oxidative DNA/RNA Damage
    • Library Preparation
      • DNA-Related Library Preparation
      • RNA-Related Library Preparation
      • Chromatin-Related Library Preparation
    • Sample Preparation
      • DNA Extraction
      • RNA Extraction
      • Chromatin Extraction
      • Histone Extraction
      • Nuclear Extraction
      • Whole Cell Extraction

    Antibodies

    • DNA Modification & Regulators
      • DNA Methylation
      • DNA Regulators
    • Histone Modification
      • Histone Methylation (Lysine)
      • Histone Methylation (Arginine)
      • Other Histone Methylation
      • Histone Acetylation
      • Histone Deacetylation
      • Other Histone Acetylation
      • Histone Phosphorylation
      • Ubiquitination & SUMOylation
      • Other Histone Antibodies
    • RNA Modification & Processing
      • RNA Methylation
      • RNA Processing
    • Chromatin & Transcription
      • Chromatin Remodeling
      • DNA Replication & Transcription
      • Cell Growth
      • Development & Differentiation
    • Cell Structure & Function
      • Cell Cycle
      • DNA Damage & Repair
      • Apoptosis & Cell Death
      • Cellular Structure
      • Trafficking
    • Signal Transduction
      • Cell Surface Receptor & Kinase
      • Intracellular Kinase & Adaptor Protein
      • Phosphatase
      • Secreted Growth Factor
    • Metabolism
      • Glucose Metabolism
      • Lipid Metabolism
      • Protein Metabolism
      • Nucleotide Metabolism
    • Immunology & Inflammation
      • Cell Marker & Receptor
      • Cytokine
      • Other Immunology Antibodies
    • Other Primary Antibodies

    • Secondary Antibodies
    • Tag Antibodies
    • Antibody Panel Packs
      • Histone Modification Panel
      • DNA Methylation Panel

    Proteins & Enzymes

    • DNA Methylation
      • DNA Methylation
      • DNA Demethylation
    • Modified Histones
      • Histone Methylation
      • Histone Demethylation
      • Histone Acetylation
      • Histone Deacetylation
      • Histone Phosphorylation
      • Histone SUMOylation
    • Unmodified Histones
    • Methylated DNA Binding
    • ADP Ribose
    • Chromatin Binding/Transcription
    • DNA Damage & Repair

    Peptides

    • Histone Methylation
    • Histone Acetylation/Deacetylation
    • Histone Phosphorylation

    Instruments

    • Sonication Devices
    • Magnets & Sample Mixers

    COVID-19 Assays

    • COVID-19 Kits
    • COVID-19 Antibodies
    • COVID-19 Proteins
  • Services

    DNA-based NGS Services

    • Reduced Representation Bisulfite Sequencing (RRBS)
    • Whole Genome Bisulfite Sequencing (WGBS)

    Chromatin-based NGS Services

    • ChIP-Seq

    ELISA-based Services

    • Global DNA 5-mC Quantification
    • Global DNA 5-hmC Quantification
    • Global RNA m6A Quantification
    • Global RNA 5-mC Quantification
    • Histone Modification Quantification
    RRBS Services
  • Support

    Technical Support

    • Submit Support Ticket
    • Download Datasheet

    Resource Bulletins

    • DNA Methylation
    • RNA Methylation
    • Chromatin Remodeling
    • Histone Modifications
    • Gene Editing
    • Miscellaneous
    • Weekly Research Showcase
  • Ordering

    Procurement

    • Ordering Info & Return Policy
    • Distributors & Resellers
    • Request a Quote
    • Application Guarantee

    Promotions

    • Current Promotional Offers
    • New Lab Startup Program
    • Risk-Free Testing: Pioneer Program
    • Rewards Program
    • Product Review Program

    Company Information

    • About Us
    • Corporate Sustainability
    • Press Releases
    • Events Calendar
    • Career Opportunities
    • Contact Us
 
EpiGentek Guarantee
   Home  »  Antibodies  »  Primary Antibodies  »  Chromatin & Transcription Antibodies  »  Development & Differentiation Antibodies 
  Quote Lookup

Development & Differentiation Antibodies

Development and differentiation includes processes by which a multicellular organism starts out from a single cell, a zygote, and gives rise to multiple cell types, forming different tissues and organs. Development comprises cell division, tissue and organ formation, body axis determination and cellular differentiation.

During development, cells must divide to form tissues and organs, while also they must differentiate into many diverse cell types with their distinctive features and functions. The totipotent zygote can give rise to all the cell types in the body and the placenta. As development progresses, cells potential to make up all cell types diminishes, and the embryonic stem cells become pluripotent, being able to give rise to all the cells of the body, except the placenta. The cells later differentiate into 3 germ layers: ectoderm, mesoderm and endoderm, and they conserve the ability to give rise to the cell types in their own lineage and not others. This is mostly under genetic control and different cell types start expressing different gene sets.

Differentiation is the process in which a cell develops its final cell type identity, and specific gene expression patterns allow the cell to synthesize RNA and protein specific for their structure and function. Not all cells in the body differentiate, some cells retain their ability to divide and produce multiple cell types. These include adult stem cells and cord blood stem cells, which are multipotent, as they have the ability to produce more than one cell type, but not all cell types. Hematopoietic stem cells are adult stem cells which give rise to the different cell types in blood. Stem cells undergo asymmetric cell division, producing two different daughter cells, one preserves the ability to self-renew and continues to be a stem cell, while the other becomes a differentiated cell.

An important group of genes controlling cellular differentiation during development are the HOX genes. They are not expressed in embryonic stem cells, but are expressed later by tissue stem cells in order to differentiate into their lineages and they are involved in determination of anterior-posterior body axis. Embryonic stem cells express transcription factors important for pluripotency, such as NANOG and OCT3/4 (POU5F1). Somatic cells can be reprogrammed to become induced pluripotent cells (iPS) by introducing transcription factors SOX2, KLF4, NANOG and OCT3/4.

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

  • No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
  • 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
  • Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
  • Trial Sizes Available: 10 & 20 µl options available for thousands of antibodies in our catalog.

Please wait...
Show More
Refine Your Results
(434)
(95)
(83)
(58)
(5)
(5)
(1)
more...
(364)
(103)
(40)
(22)
(16)
(13)
(4)
(4)
(4)
(2)
(1)
(0)
more...
(448)
(12)
(7)
(152)
(105)
(105)
(105)
(455)
(12)
(0)
(455)
(12)
(0)
(5)
(409)
(46)
(12)
(454)
(38)
(34)
(4)
(4)
(12)
(75)
CUT&LUNCH Assay Kit
Company
About Epigentek
Press Releases
Events Calendar
Corporate Sustainability
Career Opportunities
What Is Epigenetics?
Contact Us
Ordering
Ordering Info & Return Policy
Distributors & Resellers

Support
Technical Support
Download Datasheets
Resource Bulletins
Promotions & Offers
Current Promotions
New Lab Startup Program
Risk-Free Testing: Pioneer Program
Rewards Program
Product Reviews
Application Guarantee
Sign Up For Exclusive Offers
Request a Quote
Stay Informed




Terms & Conditions | Privacy Policy | Site Map
Copyright © EpigenTek Group Inc. All rights reserved.
  • Stay Informed:
Terms & Conditions | Privacy Policy Copyright © 2020 EpiGentek
➤