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Histone Deacetylase (HDAC) Assay

Histone deacetylases (HDACs), also known as lysine deacetylases (KDACs), are a class of enzymes that remove acetyl groups from core histones (H2A, H2B, H3 and H4), thereby regulating gene expression.

These epigenetic enzymes influence the structure of chromatin, the protein-DNA complex that forms into chromosomes residing in the nucleus. By removing an acetyl group, HDACs enable the tightening of the chromatin structure into what is called heterochromatin. Specifically, the DNA that wraps around the histones is more compact, which can reduce the transcription of important genes.

In contrast, histone acetyltransferases (HATs) add acetyl groups to histones and are associated with euchromatin, a loosened chromatin structure that increases transcription and gene expression. HDACs are also tightly involved in cell cycle regulation, cell proliferation, and in the development of human cancer. By studying the activity and inhibition of HDACs, researchers can gain a better understanding of the impact histone deacetylation has on diseases and various cellular processes.

Result Pages:  1  Displaying 1 to 18 (of 18 products)
Image Description Cat. No. Size Price
EpiQuik HDAC Activity/Inhibition Assay Kit (Fluorometric)
EpiQuik HDAC Activity/Inhibition Assay Kit (Fluorometric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-4001-4848 assays $194.00 Add to Cart
P-4001-9696 assays $338.00 Add to Cart
Research Kits
EpiQuik HDAC Activity/Inhibition Assay Kit (Colorimetric)
EpiQuik HDAC Activity/Inhibition Assay Kit (Colorimetric)

Citations (34) | (1)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-4002-4848 assays $194.00 Add to Cart
P-4002-9696 assays $338.00 Add to Cart
Research Kits
EpiQuik HDAC1 Assay Kit (Colorimetric)
EpiQuik HDAC1 Assay Kit (Colorimetric)

Citations (2)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4005-4848 assays $369.00 Add to Cart
P-4005-9696 assays $524.00 Add to Cart
Research Kits
EpiQuik HDAC2 Assay Kit (Colorimetric)
EpiQuik HDAC2 Assay Kit (Colorimetric)

Citations (4)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4006-4848 assays $369.00 Add to Cart
P-4006-9696 assays $524.00 Add to Cart
Research Kits
EpiQuik HDAC8 Assay Kit (Colorimetric)
EpiQuik HDAC8 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4007-4848 assays $369.00 Add to Cart
P-4007-9696 assays $524.00 Add to Cart
Research Kits
Epigenase HDAC Activity/Inhibition Direct Assay Kit (Colorimetric)
Epigenase HDAC Activity/Inhibition Direct Assay Kit (Colorimetric)

Citations (28) | (1)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-4034-4848 assays $199.00 Add to Cart
P-4034-9696 assays $359.00 Add to Cart
Research Kits
Epigenase HDAC Activity/Inhibition Direct Assay Kit (Fluorometric)
Epigenase HDAC Activity/Inhibition Direct Assay Kit (Fluorometric)

Citations (3)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-4035-4848 assays $199.00 Add to Cart
P-4035-9696 assays $369.00 Add to Cart
Research Kits
Epigenase Universal SIRT Activity/Inhibition Assay Kit (Colorimetric)
Epigenase Universal SIRT Activity/Inhibition Assay Kit (Colorimetric)

Citations (5) | (1)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-4036-4848 assays $221.00 Add to Cart
P-4036-9696 assays $399.00 Add to Cart
Research Kits
Epigenase Universal SIRT Activity/Inhibition Assay Kit (Fluorometric)
Epigenase Universal SIRT Activity/Inhibition Assay Kit (Fluorometric)

Citations (1)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-4037-4848 assays $225.00 Add to Cart
P-4037-9696 assays $399.00 Add to Cart
Research Kits
EpiQuik HDAC3 Assay Kit (Colorimetric)
EpiQuik HDAC3 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4040-4848 assays $338.00 Add to Cart
P-4040-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik HDAC4 Assay Kit (Colorimetric)
EpiQuik HDAC4 Assay Kit (Colorimetric)

Citations (3)
Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4042-4848 assays $338.00 Add to Cart
P-4042-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik HDAC5 Assay Kit (Colorimetric)
EpiQuik HDAC5 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4044-4848 assays $338.00 Add to Cart
P-4044-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik HDAC6 Assay Kit (Colorimetric)
EpiQuik HDAC6 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4046-4848 assays $338.00 Add to Cart
P-4046-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik HDAC7 Assay Kit (Colorimetric)
EpiQuik HDAC7 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4048-4848 assays $338.00 Add to Cart
P-4048-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik HDAC9 Assay Kit (Colorimetric)
EpiQuik HDAC9 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4050-4848 assays $338.00 Add to Cart
P-4050-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik HDAC10  Assay Kit (Colorimetric)
EpiQuik HDAC10 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4052-4848 assays $338.00 Add to Cart
P-4052-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik HDAC11  Assay Kit (Colorimetric)
EpiQuik HDAC11 Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Amount Quantitation
Vessel Format: 96-Well Plate
P-4054-4848 assays $338.00 Add to Cart
P-4054-9696 assays $549.00 Add to Cart
Research Kits
EpiQuik BRD2 Binding Activity/Inhibition Assay Kit (Colorimetric)
EpiQuik BRD2 Binding Activity/Inhibition Assay Kit (Colorimetric)

Input Type: Nuclear Extracts, Purified Enzyme
Research Area: Histone Acetylation
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-4058-4848 assays $318.00 Add to Cart
P-4058-9696 assays $524.00 Add to Cart
Research Kits
Result Pages:  1  Displaying 1 to 18 (of 18 products)
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