DNA/RNA Damage & Repair

DNA and RNA damage refers to the structural and functional alteration of these nucleic acids. It can be caused by several factors, including oxidative stress, genotoxic/cytotoxic agents, ionizing radiation, industrial chemicals, and cancer chemotherapy.

The Role of Oxidative Stress in DNA Damage

Oxidative stress has been identified as one of the greatest factors in DNA and RNA damage. It occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the ability of cells to detoxify or repair the resulting damage. This can lead to the formation of oxygen-based radicals that can attack and alter the nucleic acid structure.

Importance of Measuring DNA Damage

It is important to measure DNA and RNA damage as this phenomenon can lead to unregulated cell division or apoptosis, prominent traits in diseases like cancer and Alzheimer's. Understanding the mechanisms behind DNA and RNA damage can aid the development of strategies to prevent or repair this damage, potentially leading to new treatments for these and other diseases. Measurement of DNA and RNA damage can also help researchers to better understand the impacts of various harmful environmental factors on the human body, such as the effects of radiation exposure, tobacco smoke, or air pollution.

Our DNA Damage Assay Kit

Our DNA damage assay kit allows researchers to accurately measure and understand DNA damage. It is a reliable tool for studying the impacts of various environmental and genetic factors on DNA integrity.