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Histone Acetylation Quantification

Histone acetylation, including histone H3 and histone H4, is involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. Quantifying total levels of acetylated histone or levels at specific lysines will help to elucidate epigenetic regulation of gene activation, and contribute to the development of HAT or HDAC-targeted drugs.
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