Our kits deliver reliable, high-performance solutions for studying chromatin accessibility, histone modifications, and protein-DNA interactions. See the results for yourself below.
Efficient: Simultaneously screen and measure multiple histone modifications on the same plate with convenient multiplex assays.
Specific & Sensitive: Directly detect the amount change of end-product for target HMT, HDMT, and HDAC enzymes from low input amounts.
Reliable: Histone marker peak profiles of CUT&LUNCH™-enriched DNA are consistent with ENCODE ChIP-seq profiles.
Our products are trusted by leading researchers and cited in top-tier publications with high impact factors, fueling groundbreaking discoveries.
Jaccard A et al. (Sep 2023) Reductive carboxylation epigenetically instructs T cell differentiation. Nature
Jin J et. al. (Nov 2024). Human HDAC6 senses valine abundancy to regulate DNA damage. Nature
Zhang J et. al. (Sep 2015). Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis. Nat Immunol.
Chevalier C et. al. (Jul 2024). Epithelial cells maintain memory of prior infection with Streptococcus pneumoniae through di-methylation of histone H3. Nat Commun
Bayo J et. al. (Mar 2019). A comprehensive study of epigenetic alterations in hepatocellular carcinoma identifies potential therapeutic targets. J Hepatol
Soto J et. al. (Jun 2023). Reduction of Intracellular Tension and Cell Adhesion Promotes Open Chromatin Structure and Enhances Cell Reprogramming. Adv Sci (Weinh)
Tamiya H et. al. (Dec 2017). SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth. AJ Clin Invest
Roy A et. al. (Nov 2019). IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. Nat Commun.
Publication-oriented data performance
Rapid, minimal-step protocols and easy handling
Lower cost per reaction than competitors
Official replacement or money-back policy
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