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   Home  »  CUT&LUNCH 
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cut&lunch assay kit epinext finish before lunch

Accelerate Protein/DNA Enrichment—Be Done by Lunch with CUT&LUNCH

Integrating all the advantages and overcoming the drawbacks of ChIP and CUT&RUN, the EpiNext™ CUT&LUNCH (Cleavage Under Target and Liberate Unique Nucleic Complex Homogenously) Assay Kit allows for highly specific enrichment of targeted protein/DNA complexes in record time.

Extremely Fast 3‑Step Protocol

Schema of Extremely Fast 3-Step Protocol
Diagram of Extremely Fast 3-Step Protocol

Why spend days on traditional CUT&RUN or ChIP assays when you can achieve faster protein/DNA enrichment without sacrificing performance? With EpigenTek’s new CUT&LUNCH kit, you can enrich target protein/DNA complexes swiftly in just a single morning session.

  • Rapid Protocol: Complete your assay in less than 2 hours.
  • Low Non-specific Background: Only 3-5% non-specific DNA binding.
  • High Specificity & Resolution: DNA is selectively cleaved at both ends of target protein-enriched regions.
  • Cost-effective: Nearly half the price per reaction compared to traditional CUT&RUN assays.
  • No Special Software: Use existing, time-tested ChIP-seq bioinformatics pipelines for NGS data analysis.
  • CUT&LUNCH sequencing data comparison
    CUT&LUNCH outperforms CUT&RUN. Peak scores are plotted in the bar graph for 100,000 MCF-7 cells using the CUT&LUNCH assay kit from Epigentek, followed by NGS for histone H3K4me3. The traditional CUT&RUN assay was used as a comparison. CUT&LUNCH shows lower background noise and narrower peaks, indicating higher localization specificity for the target histone modification at more precisely defined regions in the genome.

Don't let lengthy protocols delay your day. Choose CUT&LUNCH for efficient, high-quality results that fit your schedule—and your budget. Enrich your protein/DNA complexes and reclaim your lunchtime!

For an all-in-one solution with library preparation conveniently streamlined in, EpigenTek offers the EpiNext™ CUT&LUNCH-Seq Kit, delivering significantly faster and more accurate results than CUT&Tag.

View CUT&LUNCH Stand-alone Kit View CUT&LUNCH-seq Kit

High Enrichment with Enhanced Specificity

Schema of Extremely Fast 3-Step Protocol
Diagram of Extremely Fast 3-Step Protocol

Outperform CUT&RUN

View CUT&LUNCH Stand-alone Kit

Outperform CUT&Tag

View CUT&LUNCH-seq Kit

Ready to Speed Up Your Chromatin Studies?

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