Global 5-mC DNA Quantification

During specific pathological, environmental, or developmental states, global DNA methylation levels can be altered in the genome. DNA hypomethylation or hypermethylation has been used as a molecular marker in numerous biological processes, including cancer. Therefore, the accurate measurement of total 5-mC levels can help epigenetic researchers to better understand the role DNA methylation plays in biological processes and the disruption of such processes.

Using an ELISA-based assay, EpiGentek’s proprietary Global 5-mC Quantification service quantifies global DNA methylation by specifically measuring 5-methylcytosine (5-mC) levels with highly accurate, reliable results. Measuring global DNA methylation status is useful for identifying the distribution of this base (5-mC) in different cell types and various areas of the genome.

Why Global 5-mC DNA
Quantification With Us?
Service #S-1GDQ
Quantitate total methylated cytosine levels in DNA on a global scale using an ELISA-like assay
End-to-End Package:
Includes everything from sample preparation to data analysis
Data Reporting Included:
Accurate readout of global 5-mC DNA levels
Rapid Turnaround Time:
3 - 5 weeks from sample submission*
Antibody-Based Processing of Samples:
Our process uses our widely used & cited MethylFlash™ Global DNA Methylation (5-mC) ELISA Easy Kit
Post-Completion Technical Support:
Complimentary high-quality support to assist with data analysis at no additional charge

*Time measured when pre-payment for service is received

**Assuming 96 isolated human DNA samples submitted

Sample Requirements

Epigenetic Services Sample Requirements
We currently accept DNA, cell, and tissue samples for our Global 5-mC Quantification service. Proper sample preparation along with the appropriate quality control methods on your end will allow the greatest chance for assay success. Please follow all guidelines for sample requirements, packaging and labeling, and shipping which are outlined on the Submission Instructions page.

Talk to a Scientist

Want more information on our Global 5-mC Quantification service or interested in customizing your research project? We’re here to help! Get in touch with one of our highly knowledgeable epigenetic services experts by calling toll-free at 1-877-374-4368 or emailing services @