Collections of high quality antibodies against select modifications.
EpiGentek's Antibody Panel Packs provide a convenient and affordable way to investigate a panel of modifications using a collection of select antibodies. Panels in each antibody pack include specific site modifications or functional modifications, such as those related to active or repressor genes.
For instance, previous research has shown that di- and tri- methylation of histone H3 on lysine 4 (H3Kme2 and H3K4me3) as well as di- and tri-methylation of histone H3 on lysine 36 (H3K36me2 and H3K36me3) is connected to gene activation. Antibody Panel Packs enable researchers to easily investigate a panel of interest.
What makes buying antibodies from EpiGentek different?
At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:
No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
Trial Sizes Available: 10 & 20 µl options available for thousands of antibodies in our catalog.
Antibody Panel Packs for investigating histone modifications, including panels for histone H3 and H4 methylation, histone H3 and H4 acetylation, and histone H3 phosphorylation. Modulation of chromatin structure via histone modification plays an important role in the regulation of transcription in eukaryotes. Euchromatin, or loosely packed chromatin, is associated with gene expression, whereas tightly coiled chromatin, or heterochromatin, is associated with gene silencing. Panels include site modifications and functional modifications, such as those related to active genes and repressor genes.
DNA methylation and demethylation are major epigenetic mechanisms that modulate gene expression in both eukaryotes and prokaryotes. Epigenetic modification 5-methylcytosine (5mC), considered the hallmark of gene silencing, has been implicated to play an important role in regulating several cellular and developmental processes, including mediating carcinogenic transformation of healthy cells. 5-hydroxymethylcytosine (5hmC) derived from enzymatic oxidization of 5mC has also been associated with many biological processes, including the pluripotency of embryonic stem cells, neuron development, and tumorigenesis in mammals.
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Collections of high quality antibodies against select modifications.
