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Cell Surface Receptor & Kinase Antibodies

Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Enzyme-linked receptors, which include the receptor tyrosine kinases, are integral membrane proteins with just one transmembrane domain spanning the plasma membrane, and with extracellular and intracellular domains. Upon binding to its ligands or secreted factors they homodimerize or heterodimerize with other members of their receptor family. This promotes conformational changes that induce the tyrosine kinase enzyme activity of the receptor, which then phosphorylates itself and its partner conveying an intracellular signal. The epidermal growth factor receptor (EGFR), the fibroblast growth factor receptor (FGFR) and insulin growth factor receptor (IGFR) are well-known families of tyrosine receptor kinases, which control cellular growth and proliferation and cellular metabolism.

G-protein coupled receptors are seven transmembrane-spanning proteins that can bind hormones, neurotransmitters and other molecules, and are mostly involved in sensory perception. They are coupled intracellularly to G-proteins, which then mediate the signal after receptor and ligand binding. The cyclicAMP receptors, frizzled/smoothened receptors and glutamate receptors are examples of G-protein coupled receptors. Ion channel-linked receptors, also called ligand-gated ion channels or ionotropic receptors, are multipass transmembrane proteins and possess channels for the transport of ions, such as Ca2+, Na+, Cl-, and K+ across membranes. They allow transduction of a fast signal generally induced by neurotransmitters in neurons.
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 601 products)
Image Description Cat. No. Size Price
ACVR1B Polyclonal Antibody
ACVR1B Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58006-05050 µg $249.00 Add to Cart
A58006-100100 µg $349.00 Add to Cart
Antibodies
ACVR1B Polyclonal Antibody, Biotin Conjugated
ACVR1B Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58007-05050 µg $249.00 Add to Cart
A58007-100100 µg $349.00 Add to Cart
Antibodies
ACVR1B Polyclonal Antibody, FITC Conjugated
ACVR1B Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58008-05050 µg $249.00 Add to Cart
A58008-100100 µg $349.00 Add to Cart
Antibodies
ACVR1B Polyclonal Antibody, HRP Conjugated
ACVR1B Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58009-05050 µg $249.00 Add to Cart
A58009-100100 µg $349.00 Add to Cart
Antibodies
ADGRA3 Polyclonal Antibody
ADGRA3 Polyclonal Antibody

Application: ELISA, IF
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66026-05050 µg $249.00 Add to Cart
A66026-100100 µg $349.00 Add to Cart
Antibodies
ADGRA3 Polyclonal Antibody, Biotin Conjugated
ADGRA3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66029-05050 µg $249.00 Add to Cart
A66029-100100 µg $349.00 Add to Cart
Antibodies
ADGRA3 Polyclonal Antibody, FITC Conjugated
ADGRA3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66028-05050 µg $249.00 Add to Cart
A66028-100100 µg $349.00 Add to Cart
Antibodies
ADGRA3 Polyclonal Antibody, HRP Conjugated
ADGRA3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66027-05050 µg $249.00 Add to Cart
A66027-100100 µg $349.00 Add to Cart
Antibodies
ADGRL4 Polyclonal Antibody
ADGRL4 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58026-05050 µg $249.00 Add to Cart
A58026-100100 µg $349.00 Add to Cart
Antibodies
ADGRL4 Polyclonal Antibody, Biotin Conjugated
ADGRL4 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58027-05050 µg $249.00 Add to Cart
A58027-100100 µg $349.00 Add to Cart
Antibodies
ADGRL4 Polyclonal Antibody, FITC Conjugated
ADGRL4 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58028-05050 µg $249.00 Add to Cart
A58028-100100 µg $349.00 Add to Cart
Antibodies
ADGRL4 Polyclonal Antibody, HRP Conjugated
ADGRL4 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A58029-05050 µg $249.00 Add to Cart
A58029-100100 µg $349.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody
ADORA1 Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62058-05050 µg $249.00 Add to Cart
A62058-100100 µg $349.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody, Biotin Conjugated
ADORA1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62061-05050 µg $249.00 Add to Cart
A62061-100100 µg $349.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody, FITC Conjugated
ADORA1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62060-05050 µg $249.00 Add to Cart
A62060-100100 µg $349.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody, HRP Conjugated
ADORA1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62059-05050 µg $249.00 Add to Cart
A62059-100100 µg $349.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody
Adrb2 Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Rat
A57241-05050 µg $249.00 Add to Cart
A57241-100100 µg $349.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody, Biotin Conjugated
Adrb2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Rat
A57244-05050 µg $249.00 Add to Cart
A57244-100100 µg $349.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody, FITC Conjugated
Adrb2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Rat
A57243-05050 µg $249.00 Add to Cart
A57243-100100 µg $349.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody, HRP Conjugated
Adrb2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Rat
A57242-05050 µg $249.00 Add to Cart
A57242-100100 µg $349.00 Add to Cart
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 601 products)
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