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Nucleotide Metabolism Antibodies

Purine and pyrimidine nucleotides are the subunits of nucleic acids, DNA and RNA, and are the precursors of nucleotide cofactors, such as NAD. Nucleotide metabolism involves the synthesis and degradation of nucleotides, which are formed from a phosphate, pentose sugar (ribose or 2-deoxyribose), and a nitrogenous base (a purine or pyrimidine). Two major pathways are involved in the synthesis of nucleotides, the de novo pathway and the salvage pathway. Nucleotides are synthesized by the de novo pathway using amino acids, CO2, and tetrahydrofolate. The salvage pathway interconverts nucleosides and nucleotides and recycles purine and pyrimidine bases released as by-products from the breakdown of nucleotides and cofactors during cellular metabolism. The salvage pathway uses a smaller amount of energy than the de novo synthesis pathway.

The purine bases are adenine and guanine, while the pyrimidine bases are thymine, cytosine, and uracil. They form the adenosine and guanosine nucleosides, and the thymidine, cytidine and uridine nucleosides, respectively. RNA is a polymer that can contain all the nucleotides, while DNA does not contain uridine. Adding one or more phosphates to the nucleoside forms a nucleotide. The nitrogenous base constitutes the main difference between the purine and pyrimidine nucleotides, and therefore their synthesis is catalyzed by different routes. However, purine and pyrimidine synthesis, both require the use of phosphoribosyl pyrophosphate (PRPP) which donates the ribose sugar and phosphate needed to form the nucleotide. The breakdown or catabolism of pyrimidine leads to several products, that can be used for fatty acid synthesis or enter the urea cycle; while the breakdown of purine nucleotides leads to one final product, uric acid, which is insoluble and excreted in urine. High levels of uric acid can lead to gout, which involves the accumulation of uric acid crystals in joints. Deficiency or genetic defects in the enzymes involved in nucleotide metabolism often results in several diseases, such as deficiency of adenine deaminase, which leads to severe combined immunodeficiency (SCID).
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 197 products)
Image Description Cat. No. Size Price
ACPP Polyclonal Antibody
ACPP Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A53618-05050 µg $249.00 Add to Cart
A53618-100100 µg $349.00 Add to Cart
Antibodies
ACPP Polyclonal Antibody, Biotin Conjugated
ACPP Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A53619-05050 µg $249.00 Add to Cart
A53619-100100 µg $349.00 Add to Cart
Antibodies
ADA Monoclonal Antibody [4G4-1C6]
ADA Monoclonal Antibody [4G4-1C6]

Application: ELISA, WB
Areas of Research: Cell Metabolism
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG1 Kappa
Purification: Affinity Purified
Reactivity: Human
A-6170-100100 µg $452.00 Add to Cart
Antibodies
ADA Polyclonal Antibody
ADA Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50009-05050 µg $249.00 Add to Cart
A50009-100100 µg $349.00 Add to Cart
Antibodies
ADA Polyclonal Antibody, Biotin Conjugated
ADA Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50012-05050 µg $249.00 Add to Cart
A50012-100100 µg $349.00 Add to Cart
Antibodies
ADA Polyclonal Antibody, FITC Conjugated
ADA Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50011-05050 µg $249.00 Add to Cart
A50011-100100 µg $349.00 Add to Cart
Antibodies
ADA Polyclonal Antibody, HRP Conjugated
ADA Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50010-05050 µg $249.00 Add to Cart
A50010-100100 µg $349.00 Add to Cart
Antibodies
ADAL Polyclonal Antibody
ADAL Polyclonal Antibody

Application: ELISA, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
A65254-05050 µg $249.00 Add to Cart
A65254-100100 µg $349.00 Add to Cart
Antibodies
ADAL Polyclonal Antibody, Biotin Conjugated
ADAL Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65257-05050 µg $249.00 Add to Cart
A65257-100100 µg $349.00 Add to Cart
Antibodies
ADAL Polyclonal Antibody, FITC Conjugated
ADAL Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65256-05050 µg $249.00 Add to Cart
A65256-100100 µg $349.00 Add to Cart
Antibodies
ADAL Polyclonal Antibody, HRP Conjugated
ADAL Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65255-05050 µg $249.00 Add to Cart
A65255-100100 µg $349.00 Add to Cart
Antibodies
AK1 Polyclonal Antibody
AK1 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50021-05050 µg $249.00 Add to Cart
A50021-100100 µg $349.00 Add to Cart
Antibodies
AK1 Polyclonal Antibody, Biotin Conjugated
AK1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50024-05050 µg $249.00 Add to Cart
A50024-100100 µg $349.00 Add to Cart
Antibodies
AK1 Polyclonal Antibody, FITC Conjugated
AK1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50023-05050 µg $249.00 Add to Cart
A50023-100100 µg $349.00 Add to Cart
Antibodies
AK1 Polyclonal Antibody, HRP Conjugated
AK1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A50022-05050 µg $249.00 Add to Cart
A50022-100100 µg $349.00 Add to Cart
Antibodies
ATIC Polyclonal Antibody
ATIC Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62126-05050 µg $249.00 Add to Cart
A62126-100100 µg $349.00 Add to Cart
Antibodies
ATIC Polyclonal Antibody, Biotin Conjugated
ATIC Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62129-05050 µg $249.00 Add to Cart
A62129-100100 µg $349.00 Add to Cart
Antibodies
ATIC Polyclonal Antibody, FITC Conjugated
ATIC Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62128-05050 µg $249.00 Add to Cart
A62128-100100 µg $349.00 Add to Cart
Antibodies
ATIC Polyclonal Antibody, HRP Conjugated
ATIC Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62127-05050 µg $249.00 Add to Cart
A62127-100100 µg $349.00 Add to Cart
Antibodies
CANT1 Polyclonal Antibody
CANT1 Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A55890-05050 µg $249.00 Add to Cart
A55890-100100 µg $349.00 Add to Cart
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 197 products)
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