BackgroundModulation of chromatin structure via histone modification plays an important role in the regulation of transcription in eukaryotes. Euchromatin, or loosely packed chromatin, is associated with gene expression, whereas tightly coiled chromatin, or heterochromatin, is associated with gene silencing. Previous research has shown that di- and tri- methylation of histone H3 on lysine 4 as well as di- and tri-methylation of histone H3 on lysine 36 is connected to gene activation.
DescriptionEpiGentek's Antibody Panel Packs provide a convenient way to investigate a panel of modifications using a collection of select antibodies. The Histone H3 Methylation Antibody Panel Pack I - Active Genes is a complete set of 4 vials for the investigation of active genes, plus a bonus vial of secondary antibody is also included:
StorageVaries. Please see user guide for recommended storage conditions for each antibody.