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Histone H3K36me3 (H3K36 Trimethyl) Polyclonal Antibody

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Citations (4) | Write a Review
Western blot analysis of Histone H3K36me3 Polyclonal Antibody.
Dot-blot analysis Histone H3K36me3 Polyclonal Antibody.
Immunohistochemistry of Histone H3K36me3 Polyclonal Antibody
Immunohistochemistry of Histone H3K36me3 Polyclonal Antibody
Immunohistochemistry of Histone H3K36me3 Polyclonal Antibody
Immunohistochemistry of Histone H3K36me3 Polyclonal Antibody
Immunohistochemistry of Histone H3K36me3 Polyclonal Antibody
Immunohistochemistry of Histone H3K36me3 Polyclonal Antibody
Chromatin immunoprecipitation Histone H3K36me3 Polyclonal Antibody
Application: ChIP, ChIPseq, IF, IHC, IP, WB
Areas of Research: Histone Methylation & Demethylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Broad Range, Human, Mouse, Rat
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-4042-02525 µl $147.00 
A-4042-05050 µl $285.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Description
Histone H3K36me3 (H3K36 Trimethyl) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Broad Range, Mouse, Rat, Human

Isotype
IgG

Uniprot ID
Q16695

Purification
Affinity Purified

Immunogen
Synthetic Peptide of Human TriMethyl-Histone H3-K36

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Application
WB, IHC, IF, IP, ChIP, ChIPseq; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 ChIP 1:20 - 1:100 CHIPseq 1:20 - 1:100 

User Guide & MSDS

[User Guide]*
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Product Citations

Onyango DO et. al. (April 2016). Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res.

Creamer KM et. al. (June 2014). The Mi-2 Homolog Mit1 Actively Positions Nucleosomes within Heterochromatin To Suppress Transcription. Mol Cell Biol. 34(11):2046-61.

Schroeder EA et. al. (June 2013). Epigenetic silencing mediates mitochondria stress-induced longevity. Cell Metab. 17(6):954-64.

Ma P et. al. (February 2012). Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development. Proc Natl Acad Sci U S A. 109(8):E481-9.

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