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Embark on a journey of discovery and innovation with EpigenTek's comprehensive suite of RNA methylation kits. Our state-of-the-art technology and cutting-edge detection methods provide unprecedented accuracy and precision, allowing researchers to push the boundaries of science and pave the way for a brighter tomorrow:
RNA methylation is a chemical modification, often at the nitrogen-6 position of an adenosine residue of RNA, that changes the way it is processed and translated. m6A methylation and demethylation occur through various enzymatic processes involving writer proteins METTL3 and METTL14 and eraser proteins FTO and ALKBH5. It is one of the most common epigenetic mechanisms, exerting diverse biological effects on RNA such as:
EpigenTek's Global RNA Methylation Kits are available to assist in your exploration of RNA methylation. From directly quantifying the "fifth RNA base" N6-Methyladenosine (m6A) to measuring 5-mC RNA, our kits make it easy to determine how RNA methylation affects your research project.
EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric)
P-9005
EpiQuik m6A RNA Methylation Quantification Kit (Fluorometric)
P-9008
MethylFlash Urine N6-methyladenosine (m6A) Quantification Kit (Colorimetric)
P-9015
MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric)
P-9009
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Efficiently enrich m6A-containing RNA from low input amounts with minimal background using EpiQuik and EpiNext CUT&RUN; m6A kits. Both kits provide necessary components for m6A RNA enrichment, with the second kit including a library prep step for convenience. Enrichment can be evaluated through PCR or epitranscriptome-wide m6A profiling using Illumina or other suitable methods.
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Determine the activity of m6A methylases and demethylases in your samples with EpiGentek's Epigenase kits. Our kits include all the essential components to assess m6A methylase or demethylase activity or inhibition levels from purified enzymes or nuclear extracts.
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EpigenTek's Total RNA Isolation Kits are an efficient and cost-effective solution for isolating high-quality total RNA from mammalian cells and tissues. The resulting RNA is suitable for various applications, such as RT-PCR, cDNA synthesis, northern blotting, and more.
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