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EpiGentek Guarantee
   Home  »  Best RNA Methylation Kits 
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Best-in-class kits to empower your discovery in RNA methylation

Embark on a journey of discovery and innovation with EpigenTek's comprehensive suite of RNA methylation kits. Our state-of-the-art technology and cutting-edge detection methods provide unprecedented accuracy and precision, allowing researchers to push the boundaries of science and pave the way for a brighter tomorrow:

m6a modification diagram
  • Robust, sensitive, specific, and consistent
  • Fast, convenient, and easy
  • Competitive pricing, lab budget friendly
  • Superior tech support and customer service.

RNA methylation is a chemical modification, often at the nitrogen-6 position of an adenosine residue of RNA, that changes the way it is processed and translated. m6A methylation and demethylation occur through various enzymatic processes involving writer proteins METTL3 and METTL14 and eraser proteins FTO and ALKBH5. It is one of the most common epigenetic mechanisms, exerting diverse biological effects on RNA such as:

  • Alternative splicing
  • Stability/Decay
  • Translation
  • RNA binding protein activity
  • Structure
  • Localization

Whole Epigenome

Measure Total m6A or 5mC RNA Amounts

EpigenTek's Global RNA Methylation Kits are available to assist in your exploration of RNA methylation. From directly quantifying the "fifth RNA base" N6-Methyladenosine (m6A) to measuring 5-mC RNA, our kits make it easy to determine how RNA methylation affects your research project.

  • m6A RNA Methylation Quantification Kit (Colorimetric) P-9005

    EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric)
    P-9005

    Learn More
  • EpiQuik m6A RNA Methylation Quantification Kit (Fluorometric) P-9008

    EpiQuik m6A RNA Methylation Quantification Kit (Fluorometric)
    P-9008

    Learn More
  • MethylFlash Urine N6-methyladenosine (m6A) Quantification Kit (Colorimetric) P-9015

    MethylFlash Urine N6-methyladenosine (m6A) Quantification Kit (Colorimetric)

    P-9015

    Learn More
  • MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric) P-9009

    MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric)
    P-9009

    Learn More
EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric)
EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric)

(338+ product citations)

  • Takes less than 4 hours to complete
  • Detects as little as 10 pg of m6A
  • No cross-reactivity to unmethylated adenosine
  • Works with m6A from any species
  • Direct ELISA format
Catalog # P-9005
Learn More
EpiQuik m6A RNA Methylation Quantification Kit (Fluorometric)
EpiQuik m6A RNA Methylation Quantification Kit (Fluorometric)

(6+ product citations)

  • Start to finish in <4 hours
  • Detects as little as 5 pg of m6A
  • No cross-reactivity to unmethylated adenosine
  • Works with m6A from any species
  • Direct ELISA format
Catalog # P-9008
Learn More
Urine N6-methyladenosine (m6A) Quantification Kit
Urine N6-methyladenosine (m6A) Quantification Kit
  • Finish within 4 hours
  • Detects as little as 0.01 ng of m6A/assay well
  • Needs just 1 to 20 µl of urine, optimal of 5 µl
  • No cross-reactivity to unmethylated adenosine
  • Works with m6A from any species
  • Direct ELISA format
Catalog # P-9015
Learn More
MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric)
MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric)

(5+ product citations)

  • Finish in 2 hours 40 minutes
  • Detects as little as 0.02% of 5-mC from 200 ng of input RNA
  • Highly comparable with HPLC-MS analysis
  • No cross-reactivity to unmethylated C & 5hmC
  • Works with 5mC from any species
  • Direct ELISA format
Catalog # P-9009
Learn More

Transcriptome Specific

Enrich and Capture m6A RNA

Efficiently enrich m6A-containing RNA from low input amounts with minimal background using EpiQuik and EpiNext CUT&RUN; m6A kits. Both kits provide necessary components for m6A RNA enrichment, with the second kit including a library prep step for convenience. Enrichment can be evaluated through PCR or epitranscriptome-wide m6A profiling using Illumina or other suitable methods.

  • EpiQuik CUT&RUN m6A RNA Enrichment (MeRIP) Kit P-9018

    EpiQuik CUT&RUN; m6A RNA Enrichment (MeRIP) Kit
    P-9018

    Learn More
  • piNext CUT&RUN RNA m6A-Seq Kit P-9016

    EpiNext CUT&RUN; RNA m6A-Seq Kit
    P-9016

    Learn More
EpiQuik CUT&RUN m6A RNA Enrichment (MeRIP) Kit
EpiQuik CUT&RUN; m6A RNA Enrichment (MeRIP) Kit

(19+ product citations)

  • Start to finish in 2.5 hours
  • Yields short m6A Ab-bound fragments
  • Input RNA can be as low as 500 ng
  • Minimal non-specific background levels
  • RNA ready for library prep & sequencing
Catalog # P-9018
Learn More
EpiNext CUT&RUN RNA m6A-Seq Kit
EpiNext CUT&RUN; RNA m6A-Seq Kit

(1+ product citations)

  • Start to finish in <6 hours
  • Yields short m6A Ab-bound fragments
  • Input RNA can be as low as 500 ng
  • Minimal MeRIP/sequencing background
  • Includes cDNA library preparation components
Catalog # P-9016
Learn More

Enzymatic Activity

Easily Measure m6A Activity/Inhibition Levels

Determine the activity of m6A methylases and demethylases in your samples with EpiGentek's Epigenase kits. Our kits include all the essential components to assess m6A methylase or demethylase activity or inhibition levels from purified enzymes or nuclear extracts.

  • Epigenase m6A Demethylase Activity/Inhibition Assay Kit (Colorimetric) P-9013

    Epigenase m6A Demethylase Activity/Inhibition Assay Kit (Colorimetric)
    P-9013

    Learn More
  • Epigenase m6A Methylase Activity/Inhibition Assay Kit P-9019

    Epigenase m6A Methylase Activity/Inhibition Assay Kit
    P-9019

    Learn More
Epigenase m6A Demethylase Activity/Inhibition Assay Kit (Colorimetric)
Epigenase m6A Demethylase Activity/Inhibition Assay Kit (Colorimetric)

(3+ product citations)

  • Finish within 5 hours
  • Quantifies the specific activity of m6A demethylase
  • Detects activity from just 2 µg of nuclear extracts or 50 ng of purified enzymes
  • Extremely low background levels
  • Direct ELISA format
Catalog # P-9013
Learn More
Epigenase m6A Methylase Activity/Inhibition Assay Kit
Epigenase m6A Methylase Activity/Inhibition Assay Kit

(1+ product citations)

  • Finish within 4 hours
  • Quantifies the specific activity of m6A methylase
  • Detects activity from just 2 µg of nuclear extracts or 50 ng of purified enzymes
  • Extremely low background levels
  • Direct ELISA format
Catalog # P-9019
Learn More

RNA Extraction

Rapid, Pure, and Simple RNA Isolation

EpigenTek's Total RNA Isolation Kits are an efficient and cost-effective solution for isolating high-quality total RNA from mammalian cells and tissues. The resulting RNA is suitable for various applications, such as RT-PCR, cDNA synthesis, northern blotting, and more.

  • EpiQuik Total RNA Isolation Fast Kit P-9105

    EpiQuik Total RNA Isolation Fast Kit

    P-9105

    Learn More
  • EpiQuik Magbeads Quick RNA Isolation Kit P-9106

    EpiQuik Magbeads Quick RNA Isolation Kit

    P-9106

    Learn More
EpiQuik Total RNA Isolation Fast Kit
EpiQuik Total RNA Isolation Fast Kit
  • Classic column-based format
  • High-quality total RNA in 30 minutes
  • RNA ready for any downstream application
  • Consistent RNA yield from minimal input
Catalog # P-9105
Learn More
EpiQuik Magbeads Quick RNA Isolation Kit
EpiQuik Magbeads Quick RNA Isolation Kit
  • Rapid magnetic beads format
  • High-quality total RNA in 30 minutes
  • RNA ready for any downstream application
  • Consistent RNA yield from minimal input
Catalog # P-9106
Learn More
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