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DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

  • No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
  • 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
  • Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
  • Trial Sizes Available: 10 & 20 µg options available on over 5,000 antibodies in our catalog.

Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 219 products)
Image Description Cat. No. Size Price
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody

Application: ELISA, IH
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Goat
Isotype: IgG
Purification: Serum
Reactivity: Broad Range
A-6300-10.1 ml $433.00 Discontinued
Antibodies
APEX1 Polyclonal Antibody
APEX1 Polyclonal Antibody new product

Application: IF, IHC, WB
Areas of Research: DNA Damage & Repair Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
Trial Size Available: A71195-020
A71195-05050 µl $256.00 Add to Cart
A71195-100100 µl $359.00 Add to Cart
Antibodies
APEX1 Polyclonal Antibody
APEX1 Polyclonal Antibody new product

Application: IF, IP, WB
Areas of Research: DNA Damage & Repair Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Knockout Validated: KO
Purification: Affinity Purified
Reactivity: Human
Trial Size Available: A71196-020
A71196-05050 µl $319.00 Add to Cart
A71196-100100 µl $489.00 Add to Cart
Antibodies
APEX1 Polyclonal Antibody
APEX1 Polyclonal Antibody

Application: ChIP, ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A68301-02020 µg $99.00 Add to Cart
A68301-05050 µg $256.00 Add to Cart
A68301-100100 µg $359.00 Add to Cart
Antibodies
APEX1 Polyclonal Antibody, Biotin Conjugated
APEX1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A53393-05050 µg $256.00 Add to Cart
A53393-100100 µg $359.00 Add to Cart
Antibodies
APEX1 Polyclonal Antibody, FITC Conjugated
APEX1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A53394-05050 µg $256.00 Add to Cart
A53394-100100 µg $359.00 Add to Cart
Antibodies
APEX1 Polyclonal Antibody, HRP Conjugated
APEX1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A53395-05050 µg $256.00 Add to Cart
A53395-100100 µg $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody
BRCA1 Polyclonal Antibody new product

Application: IF, IHC, WB
Areas of Research: DNA Damage & Repair Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse
Trial Size Available: A71329-020
A71329-05050 µl $256.00 Add to Cart
A71329-100100 µl $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody
BRCA1 Polyclonal Antibody new product

Application: IF, WB
Areas of Research: DNA Damage & Repair Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse
Trial Size Available: A71330-020
A71330-05050 µl $256.00 Add to Cart
A71330-100100 µl $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody
BRCA1 Polyclonal Antibody new product

Application: IF, IHC, WB
Areas of Research: DNA Damage & Repair Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A71331-020
A71331-05050 µl $256.00 Add to Cart
A71331-100100 µl $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody
BRCA1 Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A54101-02020 µg $99.00 Add to Cart
A54101-05050 µg $256.00 Add to Cart
A54101-100100 µg $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody
BRCA1 Polyclonal Antibody new product

Application: IF, IHC, WB
Areas of Research: DNA Damage & Repair Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A71332-020
A71332-05050 µl $256.00 Add to Cart
A71332-100100 µl $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody, Biotin Conjugated
BRCA1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54104-05050 µg $256.00 Add to Cart
A54104-100100 µg $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody, FITC Conjugated
BRCA1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54103-05050 µg $256.00 Add to Cart
A54103-100100 µg $359.00 Add to Cart
Antibodies
BRCA1 Polyclonal Antibody, HRP Conjugated
BRCA1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54102-05050 µg $256.00 Add to Cart
A54102-100100 µg $359.00 Add to Cart
Antibodies
BRCC3 Polyclonal Antibody
BRCC3 Polyclonal Antibody new product

Application: WB
Areas of Research: DNA Damage & Repair Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A71413-020
A71413-05050 µl $256.00 Add to Cart
A71413-100100 µl $359.00 Add to Cart
Antibodies
BRCC3 Polyclonal Antibody
BRCC3 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A54460-02020 µg $99.00 Add to Cart
A54460-05050 µg $256.00 Add to Cart
A54460-100100 µg $359.00 Add to Cart
Antibodies
BRCC3 Polyclonal Antibody, Biotin Conjugated
BRCC3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54461-05050 µg $256.00 Add to Cart
A54461-100100 µg $359.00 Add to Cart
Antibodies
BRCC3 Polyclonal Antibody, FITC Conjugated
BRCC3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54463-05050 µg $256.00 Add to Cart
A54463-100100 µg $359.00 Add to Cart
Antibodies
BRCC3 Polyclonal Antibody, HRP Conjugated
BRCC3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54462-05050 µg $256.00 Add to Cart
A54462-100100 µg $359.00 Add to Cart
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 219 products)
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