DNA Methylation & Demethylation Antibodies

DNA Methylation & Demethylation Antibodies focus on the proteins and molecular marks that establish, interpret, and reverse cytosine methylation states. DNA methylation at CpG sites can contribute to transcriptional repression, imprinting, repetitive element control, X-chromosome inactivation, genome stability, and long-term regulation of cell identity, while active and passive demethylation mechanisms reshape these patterns.

This group includes targets connected to DNMT enzymes, TET-mediated oxidation pathways, methyl-CpG binding proteins, hydroxymethylation biology, and DNA-associated regulators that link methylation status with chromatin function. These antibodies support analysis of how DNA modification patterns influence gene expression, development, cancer epigenetics, cellular reprogramming, and disease-associated regulatory changes.