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Phosphatase Antibodies

Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Two important phosphatases include the serine/threonine protein phosphatase 2A (PP2A) and phosphatase and tensin homolog (PTEN). PP2A is a key phosphatase as it catalyzes dephosphorylation of many proteins, but also dephosphorylates the main protein kinases responsible for activation of major signaling pathways, including AKT, ERK MAP kinase and Protein kinase C (PKC) family members. PTEN dephosphorylates proteins, as well as the phospholipid phosphatidylinositol (3,4,5)-trisphosphate (PIP3), which induces inhibition of signaling by AKT, a critical pathway involved in cellular growth and proliferation. PTEN is a tumor suppressor frequently mutated and involved in the pathogenesis and progression of several cancers.
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PPM1K Polyclonal Antibody
PPM1K Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A66354-02020 µg $59.00 Add to Cart
A66354-05050 µg $256.00 Add to Cart
A66354-100100 µg $359.00 Add to Cart
Antibodies
PPM1K Polyclonal Antibody, Biotin Conjugated
PPM1K Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66357-05050 µg $256.00 Add to Cart
A66357-100100 µg $359.00 Add to Cart
Antibodies
PPM1K Polyclonal Antibody, FITC Conjugated
PPM1K Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66356-05050 µg $256.00 Add to Cart
A66356-100100 µg $359.00 Add to Cart
Antibodies
PPM1K Polyclonal Antibody, HRP Conjugated
PPM1K Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66355-05050 µg $256.00 Add to Cart
A66355-100100 µg $359.00 Add to Cart
Antibodies
PPM1M Polyclonal Antibody
PPM1M Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A60378-02020 µg $59.00 Add to Cart
A60378-05050 µg $256.00 Add to Cart
A60378-100100 µg $359.00 Add to Cart
Antibodies
PPM1M Polyclonal Antibody, Biotin Conjugated
PPM1M Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A60379-05050 µg $256.00 Add to Cart
A60379-100100 µg $359.00 Add to Cart
Antibodies
PPM1M Polyclonal Antibody, FITC Conjugated
PPM1M Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A60380-05050 µg $256.00 Add to Cart
A60380-100100 µg $359.00 Add to Cart
Antibodies
PPM1M Polyclonal Antibody, HRP Conjugated
PPM1M Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A60381-05050 µg $256.00 Add to Cart
A60381-100100 µg $359.00 Add to Cart
Antibodies
PPME1 Polyclonal Antibody
PPME1 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A50424-02020 µg $59.00 Add to Cart
A50424-05050 µg $256.00 Add to Cart
A50424-100100 µg $359.00 Add to Cart
Antibodies
PPME1 Polyclonal Antibody, Biotin Conjugated
PPME1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50427-05050 µg $256.00 Add to Cart
A50427-100100 µg $359.00 Add to Cart
Antibodies
PPME1 Polyclonal Antibody, FITC Conjugated
PPME1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50426-05050 µg $256.00 Add to Cart
A50426-100100 µg $359.00 Add to Cart
Antibodies
PPME1 Polyclonal Antibody, HRP Conjugated
PPME1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50425-05050 µg $256.00 Add to Cart
A50425-100100 µg $359.00 Add to Cart
Antibodies
PPP1CC Polyclonal Antibody
PPP1CC Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A63202-02020 µg $59.00 Add to Cart
A63202-05050 µg $256.00 Add to Cart
A63202-100100 µg $359.00 Add to Cart
Antibodies
PPP1CC Polyclonal Antibody, Biotin Conjugated
PPP1CC Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A63205-05050 µg $256.00 Add to Cart
A63205-100100 µg $359.00 Add to Cart
Antibodies
PPP1CC Polyclonal Antibody, FITC Conjugated
PPP1CC Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A63204-05050 µg $256.00 Add to Cart
A63204-100100 µg $359.00 Add to Cart
Antibodies
PPP1CC Polyclonal Antibody, HRP Conjugated
PPP1CC Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A63203-05050 µg $256.00 Add to Cart
A63203-100100 µg $359.00 Add to Cart
Antibodies
PPP1R11 Polyclonal Antibody
PPP1R11 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A51549-02020 µg $59.00 Add to Cart
A51549-05050 µg $256.00 Add to Cart
A51549-100100 µg $359.00 Add to Cart
Antibodies
PPP1R11 Polyclonal Antibody, Biotin Conjugated
PPP1R11 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51552-05050 µg $256.00 Add to Cart
A51552-100100 µg $359.00 Add to Cart
Antibodies
PPP1R11 Polyclonal Antibody, FITC Conjugated
PPP1R11 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51551-05050 µg $256.00 Add to Cart
A51551-100100 µg $359.00 Add to Cart
Antibodies
PPP1R11 Polyclonal Antibody, HRP Conjugated
PPP1R11 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51550-05050 µg $256.00 Add to Cart
A51550-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 61 to 80 (of 182 products)
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