BackgroundFunctions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
DescriptionCDC25C Recombinant Monoclonal Antibody [3E6]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP30307
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human CDC25C
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesM-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C
ApplicationELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
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