BackgroundTyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
DescriptionCDC25B Recombinant Monoclonal Antibody [3D6]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP30305
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human CDC25B
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesM-phase inducer phosphatase 2, Dual specificity phosphatase Cdc25B, CDC25B, CDC25HU2
ApplicationELISA
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