DNMT3B Polyclonal Antibody

Background
DNMT3B has been demonstrated to methylate both unmethylated andhemimethylated DNA equally and is supposed to mediate de novo methylationtogether with Dnmt1. Increased activation or amount of Dnmt3b is believed to be involved in carcinogenesis, as well as other genetic and epigenetic diseases.

Description
DNMT3B Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
Q9UBC3

Purification
Affinity Purification

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 345-475 of human DNMT3B (Q9UBC3).

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
Cytosine 5methyltransferase 3B antibody, DNA (cytosine 5) methyltransferase 3 beta antibody, DNA (cytosine-5)-methyltransferase 3B antibody, DNA antibody, DNA methyltransferase HsaIIIB antibody, DNA MTase HsaIIIB antibody, DNM3B_HUMAN antibody, Dnmt3b antibody, EC 2.1.1.37 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MGC124407 antibody, RP23-89H14.3 antibody

Application
WB, IF; Recommended dilution: WB: 1:200-1:1000, IF:1:50-1:200