BackgroundDNMT3B has been demonstrated to methylate both unmethylated andhemimethylated DNA equally and is supposed to mediate de novo methylationtogether with Dnmt1. Increased activation or amount of Dnmt3b is believed to be involved in carcinogenesis, as well as other genetic and epigenetic diseases.
DescriptionDNMT3B Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ9UBC3
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 345-475 of human DNMT3B (Q9UBC3).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesCytosine 5methyltransferase 3B antibody, DNA (cytosine 5) methyltransferase 3 beta antibody, DNA (cytosine-5)-methyltransferase 3B antibody, DNA antibody, DNA methyltransferase HsaIIIB antibody, DNA MTase HsaIIIB antibody, DNM3B_HUMAN antibody, Dnmt3b antibody, EC 2.1.1.37 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MGC124407 antibody, RP23-89H14.3 antibody
ApplicationWB, IF; Recommended dilution: WB: 1:200-1:1000, IF:1:50-1:200
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![DNMT1 Monoclonal Antibody [60B1220.1]](images/a1001data1.gif "DNMT1 Monoclonal Antibody [60B1220.1]")
