Product Overview
Background
DNMT3B has been demonstrated to methylate both unmethylated and hemimethylated DNA equally and is supposed to mediate de novo methylation together with Dnmt1. Increased activation or amount of Dnmt3b is believed to be involved in carcinogenesis, as well as other genetic and epigenetic diseases.
Description
DNMT3B Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Specificity
Human, Mouse
Isotype
IgG
Uniprot ID
Q9UBC3
Purification
Affinity Purified
Immunogen
Synthetic Peptide of Human DNMT3B
Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.
Alternative Names
Cytosine 5methyltransferase 3B antibody, DNA (cytosine 5) methyltransferase 3 beta antibody, DNA (cytosine-5)-methyltransferase 3B antibody, DNA antibody, DNA methyltransferase HsaIIIB antibody, DNA MTase HsaIIIB antibody, DNM3B_HUMAN antibody, Dnmt3b antibody, EC 2.1.1.37 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MGC124407 antibody, RP23-89H14.3 antibody
Application
WB