BackgroundDNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
DescriptionDNMT1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman
IsotypeIgG
PurificationAffinity Purified
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 760-1109 of DNMT1 (NP_001370.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesAIM, DNMT, MCMT, CXXC9, HSN1E, ADCADN
ApplicationWB, IF, IP; Recommended dilution: WB: 1:500-1:2000, IF:1:50-1:200, IP:1:50-1:100
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![5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]](images/a1014data1.gif "5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]")
