SUV39H1 Monoclonal Antibody

Background
SUV39H1 is a human homologue of the dominant Drosophila PEV modifier Su(var)3-9and is composed of 412 amino acid residues. SUV39H1, as a histone methyltransferase, selectively methylates histone H3 on lysine 9, which generates a binding site for HP1proteins. HP1 proteins are a family of heterochromatic adaptor molecules involved in bothgene silencing and supra-nucleosomal chromatin structure. SUV39H1 plays in importantrole in histone modification and regulation of gene expression.

Description
SUV39H1 Monoclonal Antibody. Unconjugated. Raised in: Mouse.

Formulation
Liquid. PBS with 0.02% sodium azide, pH7.3.

Specificity
Human, Mouse

Isotype
IgG

Purification
Affinity Purified

Immunogen
Synthetic Peptide of Human SUV39H1

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
H3 K9 HMTase1 antibody, Histone H3 K9 methylation antibody, Histone H3 Lys 9 methylation antibody, Histone H3-K9 methyltransferase 1 antibody, KMT1 A antibody, KMT1A antibody, Lysine N methyltransferase 1A antibody, MG44 antibody, mIS6 antibody, Position-effect variegation 3-9 homolog antibody, Su(var)3 9 homolog 1 antibody, Suppressor of variegation 3 9 homolog 1 (Drosophila) antibody

Application
WB; Recommended dilution: WB 1:500 - 1:1000