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PRMT6 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human testis tissue using PRMT6 Polyclonal Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using PRMT6 Polyclonal Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using PRMT6 Polyclonal Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Application: ELISA, IF, IHC
Areas of Research: Histone Methylation & Demethylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-3006-02020 µg $59.00 
A-3006-05050 µg $242.00 
A-3006-100100 µg $399.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
PRMT6, or Protein arginine N-methyltransferase 6, is part of the PRMT family that catalyzes the methylation of arginine residues. PRMT6 specifically coregulates gene expression by acting as an activator and repressor via dimethylation of Histone H3R2me2a. PRMT6 methylates several histones at various residues, particularly Histone H2AR3me, Histone H3K4me2, Histone H3K4me3, as well as Histone H4R3me. By transcriptionally repressing tumor suppressor genes, PRMT6 has been shown to regulate cell proliferation and senescence and, via interactions with Rev, Nucleocapsid protein p7, and Tat, PRMT6 might also be implicated in innate immunity against HIV-1.

Description
PRMT6 Polyclonal Antibody. Unconjugated. Raised in: Rabbit

Formulation
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4

Specificity
Human

Isotype
IgG

Uniprot ID
Q96LA8

Purification
Protein G purified

Immunogen
Recombinant Human Protein arginine N-methyltransferase 6 protein (119-375AA)

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6) (Histone-arginine N-methyltransferase PRMT6), PRMT6, HRMT1L6

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

 

VCU0006

User Guide & MSDS

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