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Signal Transduction Antibodies

Signal Transduction Antibodies

Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intracellularly. A wide range of antibodies are involved in signal transduction, such as cell surface receptor and kinase antibodies, intracellular kinase and adaptor protein antibodies, phosphatase antibodies, and secreted growth factor antibodies. Signaling pathways and their fluid dynamic processes can be studied by researchers aiming to learn more about their far-reaching morphological effects and especially their influence on the regulation of gene expression. Signal transduction antibodies can also offer insight into various pathways and their role in the development of diseases, for example, Alzheimer’s, lupus, cancer and rheumatoid arthritis.
Cell Surface Receptor & Kinase Antibodies
Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Intracellular Kinase & Adaptor Protein Antibodies
After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

Phosphatase Antibodies
Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Secreted Growth Factor Antibodies
Growth factors, peptide hormones, neurotransmitters and other secreted molecules initiate diverse signals involved in controlling cellular growth and proliferation, tissue development and differentiation, cellular metabolism and other biological processes. They initiate signals by binding to a receptor on the cell surface, which then undergoes a conformational change leading to an intracellular signaling cascade.

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ARHGDIA Polyclonal Antibody
ARHGDIA Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52636-02020 µg $99.00 Add to Cart
A52636-05050 µg $256.00 Add to Cart
A52636-100100 µg $359.00 Add to Cart
Antibodies
ARHGDIA Polyclonal Antibody, Biotin Conjugated
ARHGDIA Polyclonal Antibody, Biotin Conjugated

Application: ELISA, IF, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52633-05050 µg $256.00 Add to Cart
A52633-100100 µg $359.00 Add to Cart
Antibodies
ARHGDIA Polyclonal Antibody, FITC Conjugated
ARHGDIA Polyclonal Antibody, FITC Conjugated

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52634-05050 µg $256.00 Add to Cart
A52634-100100 µg $359.00 Add to Cart
Antibodies
ARHGDIA Polyclonal Antibody, HRP Conjugated
ARHGDIA Polyclonal Antibody, HRP Conjugated

Application: ELISA, IF, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52635-05050 µg $256.00 Add to Cart
A52635-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody
ARHGEF18 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A63334-02020 µg $99.00 Add to Cart
A63334-05050 µg $256.00 Add to Cart
A63334-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody
ARHGEF18 Polyclonal Antibody

Application: ELISA, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A51713-02020 µg $99.00 Add to Cart
A51713-05050 µg $256.00 Add to Cart
A51713-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody, Biotin Conjugated
ARHGEF18 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A63337-05050 µg $256.00 Add to Cart
A63337-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody, Biotin Conjugated
ARHGEF18 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51716-05050 µg $256.00 Add to Cart
A51716-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody, FITC Conjugated
ARHGEF18 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51715-05050 µg $256.00 Add to Cart
A51715-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody, FITC Conjugated
ARHGEF18 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A63336-05050 µg $256.00 Add to Cart
A63336-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody, HRP Conjugated
ARHGEF18 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51714-05050 µg $256.00 Add to Cart
A51714-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF18 Polyclonal Antibody, HRP Conjugated
ARHGEF18 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A63335-05050 µg $256.00 Add to Cart
A63335-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF39 Polyclonal Antibody
ARHGEF39 Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58130-02020 µg $99.00 Add to Cart
A58130-05050 µg $256.00 Add to Cart
A58130-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF39 Polyclonal Antibody, Biotin Conjugated
ARHGEF39 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58131-05050 µg $256.00 Add to Cart
A58131-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF39 Polyclonal Antibody, FITC Conjugated
ARHGEF39 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58132-05050 µg $256.00 Add to Cart
A58132-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF39 Polyclonal Antibody, HRP Conjugated
ARHGEF39 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58133-05050 µg $256.00 Add to Cart
A58133-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF7 Polyclonal Antibody
ARHGEF7 Polyclonal Antibody

Application: ELISA, IF, IP
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A53117-02020 µg $99.00 Add to Cart
A53117-05050 µg $256.00 Add to Cart
A53117-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF7 Polyclonal Antibody, Biotin Conjugated
ARHGEF7 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53114-05050 µg $256.00 Add to Cart
A53114-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF7 Polyclonal Antibody, FITC Conjugated
ARHGEF7 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53115-05050 µg $256.00 Add to Cart
A53115-100100 µg $359.00 Add to Cart
Antibodies
ARHGEF7 Polyclonal Antibody, HRP Conjugated
ARHGEF7 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53116-05050 µg $256.00 Add to Cart
A53116-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]  ... 6  7  8  9  10 ...  [Next >>]  Displaying 161 to 180 (of 2525 products)
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