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Signal Transduction Antibodies

Signal Transduction Antibodies

Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intracellularly. A wide range of antibodies are involved in signal transduction, such as cell surface receptor and kinase antibodies, intracellular kinase and adaptor protein antibodies, phosphatase antibodies, and secreted growth factor antibodies. Signaling pathways and their fluid dynamic processes can be studied by researchers aiming to learn more about their far-reaching morphological effects and especially their influence on the regulation of gene expression. Signal transduction antibodies can also offer insight into various pathways and their role in the development of diseases, for example, Alzheimer’s, lupus, cancer and rheumatoid arthritis.
Cell Surface Receptor & Kinase Antibodies
Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Intracellular Kinase & Adaptor Protein Antibodies
After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

Phosphatase Antibodies
Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Secreted Growth Factor Antibodies
Growth factors, peptide hormones, neurotransmitters and other secreted molecules initiate diverse signals involved in controlling cellular growth and proliferation, tissue development and differentiation, cellular metabolism and other biological processes. They initiate signals by binding to a receptor on the cell surface, which then undergoes a conformational change leading to an intracellular signaling cascade.

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ARHGAP11A Polyclonal Antibody
ARHGAP11A Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A65518-02020 µg $99.00 Add to Cart
A65518-05050 µg $256.00 Add to Cart
A65518-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP11A Polyclonal Antibody, Biotin Conjugated
ARHGAP11A Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65521-05050 µg $256.00 Add to Cart
A65521-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP11A Polyclonal Antibody, FITC Conjugated
ARHGAP11A Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65520-05050 µg $256.00 Add to Cart
A65520-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP11A Polyclonal Antibody, HRP Conjugated
ARHGAP11A Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65519-05050 µg $256.00 Add to Cart
A65519-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP19 Polyclonal Antibody
ARHGAP19 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A55427-02020 µg $99.00 Add to Cart
A55427-05050 µg $256.00 Add to Cart
A55427-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP19 Polyclonal Antibody, Biotin Conjugated
ARHGAP19 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55430-05050 µg $256.00 Add to Cart
A55430-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP19 Polyclonal Antibody, FITC Conjugated
ARHGAP19 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55429-05050 µg $256.00 Add to Cart
A55429-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP19 Polyclonal Antibody, HRP Conjugated
ARHGAP19 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55428-05050 µg $256.00 Add to Cart
A55428-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP25 Polyclonal Antibody
ARHGAP25 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58122-02020 µg $99.00 Add to Cart
A58122-05050 µg $256.00 Add to Cart
A58122-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP25 Polyclonal Antibody, Biotin Conjugated
ARHGAP25 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58123-05050 µg $256.00 Add to Cart
A58123-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP25 Polyclonal Antibody, FITC Conjugated
ARHGAP25 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58124-05050 µg $256.00 Add to Cart
A58124-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP25 Polyclonal Antibody, HRP Conjugated
ARHGAP25 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58125-05050 µg $256.00 Add to Cart
A58125-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP27 Polyclonal Antibody
ARHGAP27 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A65402-02020 µg $99.00 Add to Cart
A65402-05050 µg $256.00 Add to Cart
A65402-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP27 Polyclonal Antibody, Biotin Conjugated
ARHGAP27 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65405-05050 µg $256.00 Add to Cart
A65405-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP27 Polyclonal Antibody, FITC Conjugated
ARHGAP27 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65404-05050 µg $256.00 Add to Cart
A65404-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP27 Polyclonal Antibody, HRP Conjugated
ARHGAP27 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65403-05050 µg $256.00 Add to Cart
A65403-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP29 Polyclonal Antibody
ARHGAP29 Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58126-02020 µg $99.00 Add to Cart
A58126-05050 µg $256.00 Add to Cart
A58126-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP29 Polyclonal Antibody, Biotin Conjugated
ARHGAP29 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58127-05050 µg $256.00 Add to Cart
A58127-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP29 Polyclonal Antibody, FITC Conjugated
ARHGAP29 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58128-05050 µg $256.00 Add to Cart
A58128-100100 µg $359.00 Add to Cart
Antibodies
ARHGAP29 Polyclonal Antibody, HRP Conjugated
ARHGAP29 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58129-05050 µg $256.00 Add to Cart
A58129-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]  ... 6  7  8  9  10 ...  [Next >>]  Displaying 141 to 160 (of 2525 products)
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