Product Overview
Background
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
Description
ANO2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
Specificity
Human, Rat
Isotype
IgG
Uniprot ID
Q9NQ90
Purification
>95%, Protein G purified
Immunogen
Recombinant Human Anoctamin-2 protein (1-83AA)
Storage
Shipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names
Anoctamin-2, Transmembrane protein 16B, ANO2, C12orf3, TMEM16B
Application
ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500