Epigentek Home
 
EpiGentek Guarantee
Refine Your Results
MethylFlash ELISA Easy
Signal Transduction Antibodies

Signal Transduction Antibodies

Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intracellularly. A wide range of antibodies are involved in signal transduction, such as cell surface receptor and kinase antibodies, intracellular kinase and adaptor protein antibodies, phosphatase antibodies, and secreted growth factor antibodies. Signaling pathways and their fluid dynamic processes can be studied by researchers aiming to learn more about their far-reaching morphological effects and especially their influence on the regulation of gene expression. Signal transduction antibodies can also offer insight into various pathways and their role in the development of diseases, for example, Alzheimer’s, lupus, cancer and rheumatoid arthritis.
Cell Surface Receptor & Kinase Antibodies
Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Intracellular Kinase & Adaptor Protein Antibodies
After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

Phosphatase Antibodies
Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Secreted Growth Factor Antibodies
Growth factors, peptide hormones, neurotransmitters and other secreted molecules initiate diverse signals involved in controlling cellular growth and proliferation, tissue development and differentiation, cellular metabolism and other biological processes. They initiate signals by binding to a receptor on the cell surface, which then undergoes a conformational change leading to an intracellular signaling cascade.

Result Pages: [<< Prev]  ... 11  12  13  14  15 ...  [Next >>]  Displaying 201 to 220 (of 2525 products)
Avpr1a Polyclonal Antibody
Avpr1a Polyclonal Antibody

Citations (1)
Application: ELISA, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: Yes
A53272-02020 µg $99.00 Add to Cart
A53272-05050 µg $256.00 Add to Cart
A53272-100100 µg $359.00 Add to Cart
Antibodies
Avpr1a Polyclonal Antibody, Biotin Conjugated
Avpr1a Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A53269-05050 µg $256.00 Add to Cart
A53269-100100 µg $359.00 Add to Cart
Antibodies
Avpr1a Polyclonal Antibody, FITC Conjugated
Avpr1a Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A53270-05050 µg $256.00 Add to Cart
A53270-100100 µg $359.00 Add to Cart
Antibodies
Avpr1a Polyclonal Antibody, HRP Conjugated
Avpr1a Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A53271-05050 µg $256.00 Add to Cart
A53271-100100 µg $359.00 Add to Cart
Antibodies
Avpr1b Polyclonal Antibody
Avpr1b Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
Trial Size Available: Yes
A53413-02020 µg $99.00 Add to Cart
A53413-05050 µg $256.00 Add to Cart
A53413-100100 µg $359.00 Add to Cart
Antibodies
Avpr1b Polyclonal Antibody, Biotin Conjugated
Avpr1b Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A53416-05050 µg $256.00 Add to Cart
A53416-100100 µg $359.00 Add to Cart
Antibodies
Avpr1b Polyclonal Antibody, FITC Conjugated
Avpr1b Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A53415-05050 µg $256.00 Add to Cart
A53415-100100 µg $359.00 Add to Cart
Antibodies
Avpr1b Polyclonal Antibody, HRP Conjugated
Avpr1b Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A53414-05050 µg $256.00 Add to Cart
A53414-100100 µg $359.00 Add to Cart
Antibodies
BAIAP3 Polyclonal Antibody
BAIAP3 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A68467-02020 µg $99.00 Add to Cart
A68467-05050 µg $249.00 Add to Cart
A68467-100100 µg $399.00 Add to Cart
Antibodies
BAIAP3 Polyclonal Antibody, Biotin Conjugated
BAIAP3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68470-05050 µg $249.00 Add to Cart
A68470-100100 µg $399.00 Add to Cart
Antibodies
BAIAP3 Polyclonal Antibody, FITC Conjugated
BAIAP3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68469-05050 µg $249.00 Add to Cart
A68469-100100 µg $399.00 Add to Cart
Antibodies
BAIAP3 Polyclonal Antibody, HRP Conjugated
BAIAP3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68468-05050 µg $249.00 Add to Cart
A68468-100100 µg $399.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody
BDNF Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58250-02020 µg $99.00 Add to Cart
A58250-05050 µg $256.00 Add to Cart
A58250-100100 µg $359.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody
BDNF Polyclonal Antibody

Application: ELISA, WB
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
Trial Size Available: Yes
A53065-02020 µg $99.00 Add to Cart
A53065-05050 µg $256.00 Add to Cart
A53065-100100 µg $359.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody
BDNF Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A52601-02020 µg $99.00 Add to Cart
A52601-05050 µg $256.00 Add to Cart
A52601-100100 µg $359.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody, Biotin Conjugated
BDNF Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A53068-05050 µg $256.00 Add to Cart
A53068-100100 µg $359.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody, Biotin Conjugated
BDNF Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52604-05050 µg $256.00 Add to Cart
A52604-100100 µg $359.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody, Biotin Conjugated
BDNF Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58251-05050 µg $256.00 Add to Cart
A58251-100100 µg $359.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody, FITC Conjugated
BDNF Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52603-05050 µg $256.00 Add to Cart
A52603-100100 µg $359.00 Add to Cart
Antibodies
BDNF Polyclonal Antibody, FITC Conjugated
BDNF Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58252-05050 µg $256.00 Add to Cart
A58252-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]  ... 11  12  13  14  15 ...  [Next >>]  Displaying 201 to 220 (of 2525 products)
Terms & Conditions | Privacy Policy | Site Map
Copyright © 2019 EpiGentek Group Inc. All rights reserved.