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BisulPlus Loci 5mC & 5hmC Detection PCR kit

Signal Transduction Antibodies

Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intracellularly. A wide range of antibodies are involved in signal transduction, such as cell surface receptor and kinase antibodies, intracellular kinase and adaptor protein antibodies, phosphatase antibodies, and secreted growth factor antibodies. Signaling pathways and their fluid dynamic processes can be studied by researchers aiming to learn more about their far-reaching morphological effects and especially their influence on the regulation of gene expression. Signal transduction antibodies can also offer insight into various pathways and their role in the development of diseases, for example, Alzheimer’s, lupus, cancer and rheumatoid arthritis.

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

  • No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
  • 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
  • Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
  • Trial Sizes Available: 10 & 20 µg options available on over 5,000 antibodies in our catalog.

Cell Surface Receptor & Kinase Antibodies
Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Intracellular Kinase & Adaptor Protein Antibodies
After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

Phosphatase Antibodies
Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Secreted Growth Factor Antibodies
Growth factors, peptide hormones, neurotransmitters and other secreted molecules initiate diverse signals involved in controlling cellular growth and proliferation, tissue development and differentiation, cellular metabolism and other biological processes. They initiate signals by binding to a receptor on the cell surface, which then undergoes a conformational change leading to an intracellular signaling cascade.

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BMP3 Polyclonal Antibody
BMP3 Polyclonal Antibody new product

Application: IHC, WB
Areas of Research: Secreted Growth Factor Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A71005-020
A71005-05050 µl $256.00 Add to Cart
A71005-100100 µl $359.00 Add to Cart
Antibodies
BMP3 Polyclonal Antibody
BMP3 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52753-02020 µg $99.00 Add to Cart
A52753-05050 µg $256.00 Add to Cart
A52753-100100 µg $359.00 Add to Cart
Antibodies
BMP3 Polyclonal Antibody, Biotin Conjugated
BMP3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52756-05050 µg $256.00 Add to Cart
A52756-100100 µg $359.00 Add to Cart
Antibodies
BMP3 Polyclonal Antibody, FITC Conjugated
BMP3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52754-05050 µg $256.00 Add to Cart
A52754-100100 µg $359.00 Add to Cart
Antibodies
BMP3 Polyclonal Antibody, HRP Conjugated
BMP3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52755-05050 µg $256.00 Add to Cart
A52755-100100 µg $359.00 Add to Cart
Antibodies
BMP4 Polyclonal Antibody
BMP4 Polyclonal Antibody new product

Application: IF, IHC, WB
Areas of Research: Secreted Growth Factor Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A71574-020
A71574-05050 µl $256.00 Add to Cart
A71574-100100 µl $359.00 Add to Cart
Antibodies
BMP4 Polyclonal Antibody
BMP4 Polyclonal Antibody new product

Application: IF, WB
Areas of Research: Secreted Growth Factor Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A71575-020
A71575-05050 µl $256.00 Add to Cart
A71575-100100 µl $359.00 Add to Cart
Antibodies
BMP4 Polyclonal Antibody
BMP4 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Mouse, Zebrafish
Trial Size Available: Yes
A55459-02020 µg $99.00 Add to Cart
A55459-05050 µg $256.00 Add to Cart
A55459-100100 µg $359.00 Add to Cart
Antibodies
BMP4 Polyclonal Antibody
BMP4 Polyclonal Antibody new product

Application: IF, WB
Areas of Research: Secreted Growth Factor Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Rat
Trial Size Available: A71573-020
A71573-05050 µl $256.00 Add to Cart
A71573-100100 µl $359.00 Add to Cart
Antibodies
BMP4 Polyclonal Antibody, Biotin Conjugated
BMP4 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A55462-05050 µg $256.00 Add to Cart
A55462-100100 µg $359.00 Add to Cart
Antibodies
BMP4 Polyclonal Antibody, FITC Conjugated
BMP4 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A55461-05050 µg $256.00 Add to Cart
A55461-100100 µg $359.00 Add to Cart
Antibodies
BMP4 Polyclonal Antibody, HRP Conjugated
BMP4 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A55460-05050 µg $256.00 Add to Cart
A55460-100100 µg $359.00 Add to Cart
Antibodies
BMP6 Polyclonal Antibody
BMP6 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52078-02020 µg $99.00 Add to Cart
A52078-05050 µg $256.00 Add to Cart
A52078-100100 µg $359.00 Add to Cart
Antibodies
BMP6 Polyclonal Antibody
BMP6 Polyclonal Antibody new product

Application: IF, WB
Areas of Research: Secreted Growth Factor Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A70841-020
A70841-05050 µl $256.00 Add to Cart
A70841-100100 µl $359.00 Add to Cart
Antibodies
BMP6 Polyclonal Antibody, Biotin Conjugated
BMP6 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52081-05050 µg $256.00 Add to Cart
A52081-100100 µg $359.00 Add to Cart
Antibodies
BMP6 Polyclonal Antibody, FITC Conjugated
BMP6 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52080-05050 µg $256.00 Add to Cart
A52080-100100 µg $359.00 Add to Cart
Antibodies
BMP6 Polyclonal Antibody, HRP Conjugated
BMP6 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52079-05050 µg $256.00 Add to Cart
A52079-100100 µg $359.00 Add to Cart
Antibodies
BMP7 Polyclonal Antibody
BMP7 Polyclonal Antibody new product

Application: WB
Areas of Research: Secreted Growth Factor Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A70928-020
A70928-05050 µl $256.00 Add to Cart
A70928-100100 µl $359.00 Add to Cart
Antibodies
BMP7 Polyclonal Antibody
BMP7 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A52444-02020 µg $99.00 Add to Cart
A52444-05050 µg $256.00 Add to Cart
A52444-100100 µg $359.00 Add to Cart
Antibodies
BMP7 Polyclonal Antibody, Biotin Conjugated
BMP7 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52441-05050 µg $256.00 Add to Cart
A52441-100100 µg $359.00 Add to Cart
Antibodies
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