Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
NUDT11 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
>95%, Protein G purified
Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 3-beta protein (1-164AA)
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Diphosphoinositol polyphosphate phosphohydrolase 3-beta (EC:188.8.131.52), DIPP-3-beta, DIPP3-beta, hDIPP3beta, NUDT11, APS1, DIPP3B, Diadenosine 5', 5'''-P1, P6-hexaphosphate hydrolase 3-beta, Diadenosine hexaphosphate hydrolase (AMP-forming) (EC:184.108.40.206), Nucleoside diphosphate-linked moiety X motif 11, Nudix motif 11, hAps1
ELISA, WB, IHC; Recommended dilution: WB:1:500-2000, IHC:1:20-1:200