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Histone Cereal Banner
Methylation
Acetylation
HAT & HDAC
HMT & HDM
Citrullination
Phosphorylation

Don’t forget these important starters

Histone Extraction
Histone Modification Antibodies

Start your day with effortless histone modification assays!

Designed to be quick, convenient, and reliable, our kits need only 1 to 4 hours assay time and can be finished all in the morning

EpigenTek kits are packed with all the essentials you need to kickstart your histone modification research! Just like your favorite breakfast cereal that provides a quick and nourishing meal, our histone kits offer a seamless solution for your research needs. With your samples in hand, our comprehensive kits provide everything you require to achieve reliable results.

  • Simple, reliable, and consistent
  • Fast, convenient, and easy
  • Competitive pricing, lab budget friendly
  • Superior tech support and customer service

    • Histone modification research is vital for understanding gene regulation, unraveling the complexities of DNA packaging, and uncovering the mechanisms behind development, diseases, and epigenetic inheritance. It holds the key to targeted therapies, personalized medicine, and advancements in regenerative biology.

    Histone Methylation Quantification

    Quantify Histone Methylation with Our Comprehensive Kits

    Quantify histone methylation effortlessly using EpigenTek's user-friendly solutions. Our multiplex kits streamline screening and measurement of multiple histone H3 or H4 modification patterns on a single plate. Or, explore precise quantification with our simplified ELISA-like kits for measuring histone H3 or H4 methylation at specific lysines.
    » See All Histone Methylation Quantification Kits

    EpiQuik Histone H3 Modification Multiplex Assay Kit (Colorimetric)
    EpiQuik Histone H3 Modification Multiplex Assay Kit (Colorimetric)

    (32+ product citations)

    • 21 histone H3 modifications screened
    • Rapid 2.5-hour procedure
    • Detects as little as 0.5 ng/well per modification
    • Includes total histone H3 sets
    Catalog # P-3100
    Learn More
    EpiQuik Histone H4 Modification Multiplex Assay Kit (Colorimetric)
    EpiQuik Histone H4 Modification Multiplex Assay Kit (Colorimetric)

    (6+ product citations)

    • 10 histone H4 modifications screened
    • Fast 2.5-hour procedure
    • Detects as little as 0.5 ng/well per modification
    • Includes total histone H4 sets
    Catalog # P-3102
    Learn More
    EpiQuik Circulating Modified Histone H3 Multiplex Assay Kit (Colorimetric)
    EpiQuik Circulating Modified Histone H3 Multiplex Assay Kit (Colorimetric)
    • 22 circulating histone H3 modifications screened
    • Rapid 2.5-hour procedure
    • Detects as little as 0.5 ng/well per modification
    • Includes total histone H3 sets
    Catalog # P-3106
    Learn More
    EpiQuik Total Histone H3 Quantification Kit (Colorimetric)
    EpiQuik Total Histone H3 Quantification Kit (Colorimetric)

    (4+ product citations)

    • Fast 2.5-hour procedure
    • Captures histone H3 from 10 ng/well extracts
    • Includes histone H3 control
    • Flexible strip-well microplate format
    Catalog # P-3062
    Learn More

    Histone Acetylation Quantification

    Discover The Power of Histone Acetylation and Gene Regulation

    Quantify acetylated histone levels in a snap using EpigenTek’s complete series of histone acetylation quantification kits. Our colorimetric and fluorometric versions make it quick and simple to measure total levels of acetylated histones or specifically target lysine sites on histones H3 and H4. With a streamlined process that takes approximately 2.5 hours, EpigenTek's advanced kits provide you with rapid and accurate results, empowering your research in a hassle-free manner.
    » See All Histone Acetylation Quantification Kits


    EpiQuik Global Histone H3 Phosphorylation (Ser10) Assay Kit (Colorimetric) (96 assays)
    EpiQuik Total Histone H3 Acetylation Detection Fast Kit (Colorimetric)

    (1+ product citations)

    • Quick 2.5-hour procedure
    • Detects as low as 2 ng/well of H3ac
    • No need for radioactivity, electrophoresis, or chromatography
    • Flexible strip-well microplate format
    Catalog # P-4030
    Learn More
    EpiQuik Total Histone H4 Acetylation Detection Fast Kit (Colorimetric)
    EpiQuik Total Histone H4 Acetylation Detection Fast Kit (Colorimetric)

    (10+ product citations)

    • Quick 2.5-hour procedure
    • Detects as low as 2 ng/well of H4ac
    • No need for radioactivity, electrophoresis, or chromatography
    • Flexible strip-well microplate format
    Catalog # P-4032
    Learn More

    HDAC & HAT Activity/Inhibition

    Study the Impact of HAT and HDAC Activity

    HAT (histone acetyltransferase) and HDAC (histone deacetylase) are enzymes involved in the modification of histone proteins. HATs add acetyl groups to histones, while HDACs remove them, both playing crucial roles in regulating gene expression. With EpigenTek's user-friendly kits, you can easily study the activities and levels of HATs and HDACs, gaining valuable insights into chromatin structure regulation and transcriptional processes driven by histone acetylation.
    » See All Histone Deacetylase (HDAC) Kits
    » See All Histone Acetyltransferase (HAT) Kits

    EpiQuik HAT Activity/Inhibition Assay Kit
    EpiQuik HAT Activity/Inhibition Assay Kit

    (72+ product citations)

    • Quick 3-hour procedure
    • Direct measurement of HAT activity
    • No need for radioactivity, electrophoresis, or chromatography
    • Flexible strip-well microplate format
    Catalog # P-4003
    Learn More
    Epigenase HDAC Activity/Inhibition Direct Assay Kit (Colorimetric)
    Epigenase HDAC Activity/Inhibition Direct Assay Kit (Colorimetric)

    (86+ product citations)

    • Quick 3.5-hour procedure
    • Detects as little as 0.5 ng of purified HDAC enzyme
    • Detection of HDAC inhibition in vivo or in vitro
    • Flexible strip-well microplate format
    Catalog # P-4034
    Learn More

    HMT & HDM Activity/Inhibition

    Analyzing Histone Methylation Enzymatic Activity

    Histone methyltransferases (HMTs) and histone demethylases (HDMs) are enzymes that play crucial roles in the regulation of histone methylation. HMTs add methyl groups to specific lysine or arginine residues on histone proteins, while HDMs remove these methyl groups. The dynamic balance between HMT and HDM activities is essential for controlling gene expression and chromatin structure. EpigenTek offers specialized kits to measure HMT and HDM activity/inhibition, allowing researchers to gain insights into the epigenetic regulation of gene activation and potential therapeutic targets.
    » See All Histone Methyltransferase Kits
    » See All Histone Demethylase Kits

    EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K27)
    EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K27)

    (29+ product citations)

    • Rapid 3-hour procedure
    • Specific measurement of H3-K27 HMT activity
    • No need for radioactivity, electrophoresis, or chromatography
    • Flexible strip-well microplate format
    Catalog # P-3005
    Learn More
    EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K4)
    EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K4)

    (21+ product citations)

    • Rapid 3-hour procedure
    • Specific measurement of H3-K4 HMT activity
    • No need for radioactivity, electrophoresis, or chromatography
    • Flexible strip-well microplate format
    Catalog # P-3002
    Learn More
    Epigenase JMJD3/UTX Demethylase Activity/Inhibition Assay Kit (Colorimetric)
    Epigenase JMJD3/UTX Demethylase Activity/Inhibition Assay Kit (Colorimetric)

    (18+ product citations)

    • Fast 3-hour procedure
    • No need for radioactivity, electrophoresis, or chromatography
    • Detects as low as 10 ng of purified JMJD3/UTX enzyme
    • Flexible strip-well microplate format
    Catalog # P-3084
    Learn More
    Epigenase LSD1 Demethylase Activity/Inhibition Assay Kit (Colorimetric)
    Epigenase LSD1 Demethylase Activity/Inhibition Assay Kit (Colorimetric)

    (3+ product citations)

    • Rapid 3-hour procedure
    • No need for radioactivity, electrophoresis, or chromatography
    • Detects as low as 5 ng of purified LSD1 enzyme
    • Flexible strip-well microplate format
    Catalog # P-3078
    Learn More

    Histone Citrullination

    Quantitatively detect circulating histone H3cit

    Histone citrullination is an epigenetic modification that alters chromatin structure by converting histone arginine to citrulline. To aid researchers studying histone citrullination, we provide convenient and efficient solutions for quantifying total citrullinated histone H3 and total circulating histone H3 from histone extracts and total citrullination from plasma and serum (both at arginines R2, R8, R17).
    » See All Histone Citrullination Kits

    EpiQuik Histone H3 Citrullination ELISA Kit (Colorimetric)
    EpiQuik Histone H3 Citrullination ELISA Kit (Colorimetric)

    (2+ product citations)

    • Quick 3.5-hour procedure
    • Only recognizes H3cit
    • Detects as low as 0.5 ng/well from histone extracts
    • Flexible strip-well microplate format
    Catalog # P-3095
    Learn More
    EpiQuik Global Histone H3 Phosphorylation (Ser10) Assay Kit (Colorimetric) (96 assays)
    EpiQuik Circulating Histone H3 Citrullination ELISA Kit (Colorimetric)

    (3+ product citations)

    • Rapid 2.5-hour procedure
    • Only recognizes circulating H3cit
    • Detects as low as 0.5 ng/well from plasma/serum
    • Flexible strip-well microplate format
    Catalog # P-3097
    Learn More

    Histone Phosphorylation

    Fast and Easy Histone H3 Phosphorylation Measurement

    Histone phosphorylation is a crucial post-translational modification where a phosphate group is added to a histone protein. This process, conserved among eukaryotes, occurs at specific amino acid residues on the histone. EpigenTek provides rapid and user-friendly ELISA-like kits to measure histone H3 phosphorylation at serine 10, key sites associated with gene activation and cell growth.
    » See All Histone Phosphorylation Kits

    EpiQuik Global Histone H3 Phosphorylation (Ser10) Assay Kit (Colorimetric) (96 assays)
    EpiQuik Global Histone H3 Phosphorylation (Ser10) Assay Kit (Colorimetric)

    (1+ product citations)

    • Rapid 3-hour procedure
    • No need for radioactivity, electrophoresis, or chromatography
    • Captures phospho-histone H3 at ser10
    • Flexible strip-well microplate format
    Catalog # P-7002
    Learn More
    EpiQuik In Situ Histone H3 Phosphorylation (Ser10) Assay Kit
    EpiQuik In Situ Histone H3 Phosphorylation (Ser10) Assay Kit
    • Fast 3-hour procedure
    • No need for radioactivity, electrophoresis, or chromatography
    • Measures in situ phospho-histone H3 at ser10
    • Flexible strip-well microplate format
    Catalog # P-7001
    Learn More
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