BackgroundCleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
DescriptionNUDT11 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ96G61
PurificationAffinity purified
ImmunogenRecombinant Human Diphosphoinositol polyphosphate phosphohydrolase 3-beta protein (1-164AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesDiphosphoinositol polyphosphate phosphohydrolase 3-beta (EC:3.6.1.52), DIPP-3-beta, DIPP3-beta, hDIPP3beta, NUDT11, APS1, DIPP3B, Diadenosine 5', 5'''-P1, P6-hexaphosphate hydrolase 3-beta, Diadenosine hexaphosphate hydrolase (AMP-forming) (EC:3.6.1.60), Nucleoside diphosphate-linked moiety X motif 11, Nudix motif 11, hAps1
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500
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