Histone H4K16ac (Acetyl H4K16) Polyclonal Antibody

Background
Histone H4- along with H2A, H2B, and H3- is involved in the structure of chromatin in eukaryotic cells. Histone H4 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occur on the N-terminal tail domains of histone H4, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H4 is primarily acetylated at lysine 5, 8, 12, and 16.

Description
Histone H4-K16ac (Acetyl H4K16) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
P62805

Purification
Affinity Purified

Immunogen
Synthesized peptide derived from Human Histone H4 around the acetylation site of K16

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK

Application
WB, IHC, IF, ELISA; Recommended dilution: WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:5000