Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody

Background
Histone H3 along with H2A, H2B and H4 is involved in the structure of chromatin in eukaryotic cells. Histone H3 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications, including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation, occur on the N-terminal tail domains of histone H3, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H3 is primarily acetylated at lysine 9, 14, 18, 23, and can also be acetylated at lysine 56.

Description
Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Mouse, Rat, Human, Broad Range

Isotype
IgG

Uniprot ID
Q16695

Purification
Affinity Purified

Immunogen
A synthetic acetylated peptide around K56 of human Histone H3 (NP_003520.1)

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Alternative Names
H3K56ac antibody, H3K56a antibody

Application
WB, IHC, IF, IP, ChIP, ChIP-seq; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:50 - 1:200, ChIP 1:20 - 1:100, ChIP-seq 1:20 - 1:100