BackgroundThe protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
DescriptionHAT1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityMouse, Rat, Human
IsotypeIgG
Uniprot IDO14929
PurificationAffinity Purified
ImmunogenRecombinant Protein of Human HAT1
StorageShipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.
Alternative NamesHistidine aminotransferase 1 antibody, Histone acetyltransferase 1 antibody, Histone acetyltransferase type B catalytic subunit antibody, KAT1 antibody, KAT1
ApplicationWB, IHC, IF, ChIP; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, ChIP 1:50 - 1:200
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