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MethylFlash ELISA Easy
Proteins & Enzymes

Proteins & Enzymes

DNA Methylation/Demethylation Proteins
Proteins involved in DNA methylation and DNA demethylation are useful for epigenetic research applications such as enzyme kinetics, selectivity profiling, screening inhibitors, antibody production and protein arrays. DNA methyltransferases (DNMTs) are the major players that methylate DNA and are involved in various biological processes from embryonic development to tumorigenesis.

Modified Histone Proteins
These recombinant histone proteins have various site-specific and degree-specific modifications including methylation, demethylation, acetylation, deacetylation, phosphorylation, and sumoylation. Modified histone proteins play a role in a wide variety of processes including regulating gene expression. Specifically, they are implicated in diseases as a result of disrupted gene expression.

Unmodified Histone Proteins
Unmodified histone proteins such as H3 and H4 are useful for studying epigenetic mechanisms such as histone methylation, histone acetylation, and histone phosphorylation, which occur as a result of the modification to histone proteins by various enzymes. These modifications are studied because of their impact on gene regulation and numerous biological processes of organisms.

Methylated DNA Binding Proteins
Methyl-CpG binding domain proteins (MBD proteins) and proteins that interact with methyl-CpG-binding proteins are involved in the complex process of transcription regulation. Specifically, methylated DNA binding proteins play a role in transcriptional repression by preventing the access of transcription factors to target sites. They close the chromatin structure by recruiting histone deacetylases (HDACs) and histone methyltransferases (HMTs) and are central to epigenetic studies.

ADP Ribose Proteins
Poly (ADP-ribose) polymerase (PARP) proteins such as PARP1, PARP2, PARP3, and PARP4, are involved in cell signaling and cell activities such as apoptosis and DNA repair. Recent research suggests ADP ribose proteins, or PARP proteins, impact the degree of DNA methylation in various ways.

Chromatin Binding/Transcription Proteins
Chromatin binding/transcription proteins can interact directly with specific target DNA sequences to regulate gene expression. These proteins regulate transcription and chromatin structure and are implicated in numerous biological processes, especially disease development and cancer.

DNA Damage & Repair Proteins
Proteins involved in DNA damage and repair are crucial to understanding processes involved in repairing molecular lesions of the DNA, which can often lead to genetic mutations and an inability of the cell to transcribe the gene of the affected area of the DNA. DNA damage and repair proteins can be especially useful as targets for cancer therapy.

Result Pages: [<< Prev]   1  2  3  4  [Next >>]  Displaying 41 to 60 (of 70 products)
PARP2 Protein
PARP2 Protein

Expressed In: sf21 Cells
Protein Species: Human
Research Area: ADP Ribose
E54000-110 µg $419.00 Add to Cart
Proteins & Enzymes
PARP3 Protein
PARP3 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: ADP Ribose
E54001-110 µg $419.00 Add to Cart
Proteins & Enzymes
Pcaf Protein
Pcaf Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E29000-150 µg $689.00 Add to Cart
Proteins & Enzymes
PRMT4 Protein
PRMT4 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24033-120 µg $524.00 Add to Cart
Proteins & Enzymes
PRMT5 Protein
PRMT5 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24034-120 µg $524.00 Add to Cart
Proteins & Enzymes
SAP18 Protein
SAP18 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E20000-120 µg $300.00 Add to Cart
Proteins & Enzymes
SET7 Protein
SET7 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E23000-150 µg $411.00 Add to Cart
Proteins & Enzymes
SET8 Protein
SET8 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24035-150 µg $524.00 Add to Cart
Proteins & Enzymes
Sirtuin1 Protein
Sirtuin1 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24015-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin2 Protein
Sirtuin2 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24016-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin3 Protein
Sirtuin3 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24017-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin4 Protein
Sirtuin4 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24018-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin5 Protein
Sirtuin5 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24019-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin6 Protein
Sirtuin6 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24013-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin7 Protein
Sirtuin7 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24014-1100 µg $522.00 Add to Cart
Proteins & Enzymes
SMYD3 Protein
SMYD3 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24036-120 µg $524.00 Add to Cart
Proteins & Enzymes
SOD1 Protein
SOD1 Protein

Citations (1)
Expressed In: E. Coli
Protein Species: Human
Research Area: DNA Damage & Repair
E70000-125 µg $310.00 Add to Cart
Proteins & Enzymes
SOD2 Protein
SOD2 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: DNA Damage & Repair
E70001-125 µg $310.00 Add to Cart
Proteins & Enzymes
STAT3 Protein
STAT3 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Chromatin Binding & Transcription
E62006-110 µg $566.00 Add to Cart
Proteins & Enzymes
SUMO-1 Protein
SUMO-1 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Sumoylation
E28000-1100 µg $209.00 Add to Cart
Proteins & Enzymes
Result Pages: [<< Prev]   1  2  3  4  [Next >>]  Displaying 41 to 60 (of 70 products)
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Intro to Epigenetics