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Proteins & Enzymes

Proteins & Enzymes

DNA Methylation/Demethylation Proteins
Proteins involved in DNA methylation and DNA demethylation are useful for epigenetic research applications such as enzyme kinetics, selectivity profiling, screening inhibitors, antibody production and protein arrays. DNA methyltransferases (DNMTs) are the major players that methylate DNA and are involved in various biological processes from embryonic development to tumorigenesis.

Modified Histone Proteins
These recombinant histone proteins have various site-specific and degree-specific modifications including methylation, demethylation, acetylation, deacetylation, phosphorylation, and sumoylation. Modified histone proteins play a role in a wide variety of processes including regulating gene expression. Specifically, they are implicated in diseases as a result of disrupted gene expression.

Unmodified Histone Proteins
Unmodified histone proteins such as H3 and H4 are useful for studying epigenetic mechanisms such as histone methylation, histone acetylation, and histone phosphorylation, which occur as a result of the modification to histone proteins by various enzymes. These modifications are studied because of their impact on gene regulation and numerous biological processes of organisms.

Methylated DNA Binding Proteins
Methyl-CpG binding domain proteins (MBD proteins) and proteins that interact with methyl-CpG-binding proteins are involved in the complex process of transcription regulation. Specifically, methylated DNA binding proteins play a role in transcriptional repression by preventing the access of transcription factors to target sites. They close the chromatin structure by recruiting histone deacetylases (HDACs) and histone methyltransferases (HMTs) and are central to epigenetic studies.

ADP Ribose Proteins
Poly (ADP-ribose) polymerase (PARP) proteins such as PARP1, PARP2, PARP3, and PARP4, are involved in cell signaling and cell activities such as apoptosis and DNA repair. Recent research suggests ADP ribose proteins, or PARP proteins, impact the degree of DNA methylation in various ways.

Chromatin Binding/Transcription Proteins
Chromatin binding/transcription proteins can interact directly with specific target DNA sequences to regulate gene expression. These proteins regulate transcription and chromatin structure and are implicated in numerous biological processes, especially disease development and cancer.

DNA Damage & Repair Proteins
Proteins involved in DNA damage and repair are crucial to understanding processes involved in repairing molecular lesions of the DNA, which can often lead to genetic mutations and an inability of the cell to transcribe the gene of the affected area of the DNA. DNA damage and repair proteins can be especially useful as targets for cancer therapy.

Result Pages:  1  2  3  4  5  [Next >>]  Displaying 1 to 20 (of 100 products)
Image Description Cat. No. Size Price
53BP1 Protein
53BP1 Protein

Expressed In: In Vitro Wheat Germ
Protein Species: Human
Research Area: DNA Damage & Repair
E72000-110 µg $524.00 Add to Cart
Proteins & Enzymes
Aurka Protein
Aurka Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Phosphorylation
E20001-110 µg $287.00 Add to Cart
Proteins & Enzymes
Aurkb Protein
Aurkb Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Phosphorylation
E20002-110 µg $287.00 Add to Cart
Proteins & Enzymes
Aurkc Protein
Aurkc Protein

Expressed In: In Vitro Wheat Germ
Protein Species: Human
Research Area: Histone Phosphorylation
E22000-110 µg $524.00 Add to Cart
Proteins & Enzymes
BRCA2 Protein
BRCA2 Protein

Expressed In: In Vitro Wheat Germ
Protein Species: Human
Research Area: DNA Damage & Repair
E72002-110 µg $524.00 Add to Cart
Proteins & Enzymes
C-jun Protein
C-jun Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Chromatin Binding & Transcription
E60000-15 µg $287.00 Add to Cart
Proteins & Enzymes
c-Myc Protein
c-Myc Protein

Expressed In: In Vitro Wheat Germ
Protein Species: Human
Research Area: Chromatin Binding & Transcription
E62000-110 µg $524.00 Add to Cart
Proteins & Enzymes
CROP Protein
CROP Protein

Expressed In: In Vitro Wheat Germ
Protein Species: Human
Research Area: DNA Damage & Repair
E72001-110 µg $524.00 Add to Cart
Proteins & Enzymes
DNMT1 Protein
DNMT1 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: DNA Methylation
E15000-110 µg $493.00 Add to Cart
Proteins & Enzymes
DNMT3A Protein
DNMT3A Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: DNA Methylation
E11000-110 µg $493.00 Add to Cart
Proteins & Enzymes
DNMT3B Protein
DNMT3B Protein

Expressed In: sf9 Cells
Protein Species: Mouse
Research Area: DNA Methylation
E14000-110 µg $493.00 Add to Cart
Proteins & Enzymes
DOT1L Protein
DOT1L Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24029-150 µg $493.00 Add to Cart
Proteins & Enzymes
EED Protein
EED Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24030-150 µg $493.00 Add to Cart
Proteins & Enzymes
EP300 Protein
EP300 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24000-150 µg $483.00 Add to Cart
Proteins & Enzymes
EZH2 Protein
EZH2 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24031-120 µg $493.00 Add to Cart
Proteins & Enzymes
G9a Protein
G9a Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24032-150 µg $493.00 Add to Cart
Proteins & Enzymes
GADD45A Protein
GADD45A Protein

Expressed In: In Vitro Wheat Germ
Protein Species: Human
Research Area: DNA Damage & Repair
E72003-110 µg $524.00 Add to Cart
Proteins & Enzymes
GCN5 Protein
GCN5 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24001-1100 µg $483.00 Add to Cart
Proteins & Enzymes
H1 Protein
H1 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Unmodified Histone
E35000-150 µg $61.00 Add to Cart
Proteins & Enzymes
H2AFX Protein
H2AFX Protein

Expressed In: In Vitro Wheat Germ
Protein Species: Human
Research Area: Unmodified Histone
E35001-150 µg $61.00 Add to Cart
Proteins & Enzymes
Result Pages:  1  2  3  4  5  [Next >>]  Displaying 1 to 20 (of 100 products)
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