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Proteins & Enzymes

Proteins & Enzymes

DNA Methylation/Demethylation Proteins
Proteins involved in DNA methylation and DNA demethylation are useful for epigenetic research applications such as enzyme kinetics, selectivity profiling, screening inhibitors, antibody production and protein arrays. DNA methyltransferases (DNMTs) are the major players that methylate DNA and are involved in various biological processes from embryonic development to tumorigenesis.

Modified Histone Proteins
These recombinant histone proteins have various site-specific and degree-specific modifications including methylation, demethylation, acetylation, deacetylation, phosphorylation, and sumoylation. Modified histone proteins play a role in a wide variety of processes including regulating gene expression. Specifically, they are implicated in diseases as a result of disrupted gene expression.

Unmodified Histone Proteins
Unmodified histone proteins such as H3 and H4 are useful for studying epigenetic mechanisms such as histone methylation, histone acetylation, and histone phosphorylation, which occur as a result of the modification to histone proteins by various enzymes. These modifications are studied because of their impact on gene regulation and numerous biological processes of organisms.

Methylated DNA Binding Proteins
Methyl-CpG binding domain proteins (MBD proteins) and proteins that interact with methyl-CpG-binding proteins are involved in the complex process of transcription regulation. Specifically, methylated DNA binding proteins play a role in transcriptional repression by preventing the access of transcription factors to target sites. They close the chromatin structure by recruiting histone deacetylases (HDACs) and histone methyltransferases (HMTs) and are central to epigenetic studies.

ADP Ribose Proteins
Poly (ADP-ribose) polymerase (PARP) proteins such as PARP1, PARP2, PARP3, and PARP4, are involved in cell signaling and cell activities such as apoptosis and DNA repair. Recent research suggests ADP ribose proteins, or PARP proteins, impact the degree of DNA methylation in various ways.

Chromatin Binding/Transcription Proteins
Chromatin binding/transcription proteins can interact directly with specific target DNA sequences to regulate gene expression. These proteins regulate transcription and chromatin structure and are implicated in numerous biological processes, especially disease development and cancer.

DNA Damage & Repair Proteins
Proteins involved in DNA damage and repair are crucial to understanding processes involved in repairing molecular lesions of the DNA, which can often lead to genetic mutations and an inability of the cell to transcribe the gene of the affected area of the DNA. DNA damage and repair proteins can be especially useful as targets for cancer therapy.

Result Pages: [<< Prev]   1  2  3  4  [Next >>]  Displaying 21 to 40 (of 70 products)
HDAC10 Protein
HDAC10 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24003-150 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC11 Protein
HDAC11 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24004-150 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC2 Protein
HDAC2 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24005-150 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC3 Protein
HDAC3 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24006-150 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC4 Protein
HDAC4 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24007-110 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC5 Protein
HDAC5 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24008-110 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC6 Protein
HDAC6 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24009-150 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC7 Protein
HDAC7 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24010-110 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC8 Protein
HDAC8 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24011-150 µg $522.00 Add to Cart
Proteins & Enzymes
HDAC9 Protein
HDAC9 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Acetylation
E24012-110 µg $522.00 Add to Cart
Proteins & Enzymes
JARID1A Protein
JARID1A Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24020-120 µg $524.00 Add to Cart
Proteins & Enzymes
JARID1C Protein
JARID1C Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24021-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2A Protein
JMJD2A Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24022-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2B Protein
JMJD2B Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24023-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2C Protein
JMJD2C Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24024-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2D Protein
JMJD2D Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24025-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD3 Protein
JMJD3 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24026-120 µg $524.00 Add to Cart
Proteins & Enzymes
K-Ras Protein
K-Ras Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Chromatin Binding & Transcription
E60001-125 µg $310.00 Add to Cart
Proteins & Enzymes
LSD1 Protein
LSD1 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24027-150 µg $524.00 Add to Cart
Proteins & Enzymes
PARP1 Protein
PARP1 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: ADP Ribose
E53000-125 µg $310.00 Add to Cart
Proteins & Enzymes
Result Pages: [<< Prev]   1  2  3  4  [Next >>]  Displaying 21 to 40 (of 70 products)
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Intro to Epigenetics