BackgroundCrucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
DescriptionLIPA Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP38571
Purification>95%, Protein G purified
ImmunogenRecombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase protein (22-399AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCholesteryl esterase, Lipase A, Sterol esterase, LIPA
ApplicationELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-5000, IHC:1:20-1:200, IF:1:50-1:200