BackgroundCrucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
DescriptionLIPA Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP38571
PurificationProtein G purified
ImmunogenRecombinant Human Lipoyl synthase, mitochondrial protein (28-372AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCholesteryl esterase Lipase A Sterol esterase LIPA
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-5000, IHC:1:20-1:200