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Intracellular Kinase & Adaptor Protein Antibodies

After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

In the case of receptor tyrosine kinases, the intracellular domain of the receptor itself possesses tyrosine kinase activity and is able to phosphorylate and activate itself. This phosphorylated residue then serves as a docking site for adaptor proteins, which initiate activation and signaling by a cascade of protein kinases. These adaptor proteins bind the phosphorylated receptor via specific protein domains, such as SH2 and SH3 domains. These signaling pathways generally culminate in activation of transcription factors in the nucleus, which alter transcription and gene expression.

A well-known pathway of intracellular kinases is the mitogen-activated protein kinase (MAPK) pathway, which involves successive phosphorylation and activation of the serine/threonine protein kinases Ras, Raf, MEK and MAPK or extracellular signal-regulated kinase (ERK). ERK then translocates to the nucleus and activates transcription factors, such as Myc. The constitutive activation of this and other signaling pathways has been implicated in cancer progression, as the unattenuated signal can lead to uncontrolled cellular proliferation. Other important kinase signaling pathways include the phosphaditylinositol-3-phosphate kinase (PI3K) and Protein Kinase B (AKT) pathway and the p38 signaling pathways. In the case of signals mediated by G-protein coupled receptors, G-proteins are the intracellular adaptor proteins bound to the receptors cytoplasmic domain which initiate the signal. The cyclic AMP and phosphaditylinositol pathways are the major signaling pathways that mediate signaling downstream of G-protein coupled receptors.
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CSNK1A1 Polyclonal Antibody
CSNK1A1 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A54428-02020 µg $99.00 Add to Cart
A54428-05050 µg $256.00 Add to Cart
A54428-100100 µg $359.00 Add to Cart
Antibodies
CSNK1A1 Polyclonal Antibody, Biotin Conjugated
CSNK1A1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54425-05050 µg $256.00 Add to Cart
A54425-100100 µg $359.00 Add to Cart
Antibodies
CSNK1A1 Polyclonal Antibody, FITC Conjugated
CSNK1A1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54426-05050 µg $256.00 Add to Cart
A54426-100100 µg $359.00 Add to Cart
Antibodies
CSNK1A1 Polyclonal Antibody, HRP Conjugated
CSNK1A1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54427-05050 µg $256.00 Add to Cart
A54427-100100 µg $359.00 Add to Cart
Antibodies
CSNK1D Polyclonal Antibody
CSNK1D Polyclonal Antibody

Application: ELISA, IF, IHC, IP, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58682-02020 µg $99.00 Add to Cart
A58682-05050 µg $256.00 Add to Cart
A58682-100100 µg $359.00 Add to Cart
Antibodies
CSNK1D Polyclonal Antibody, Biotin Conjugated
CSNK1D Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58683-05050 µg $256.00 Add to Cart
A58683-100100 µg $359.00 Add to Cart
Antibodies
CSNK1D Polyclonal Antibody, FITC Conjugated
CSNK1D Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58684-05050 µg $256.00 Add to Cart
A58684-100100 µg $359.00 Add to Cart
Antibodies
CSNK1D Polyclonal Antibody, HRP Conjugated
CSNK1D Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58685-05050 µg $256.00 Add to Cart
A58685-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody
CSNK1E Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52740-02020 µg $99.00 Add to Cart
A52740-05050 µg $256.00 Add to Cart
A52740-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody
CSNK1E Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A56246-02020 µg $99.00 Add to Cart
A56246-05050 µg $256.00 Add to Cart
A56246-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody, Biotin Conjugated
CSNK1E Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52737-05050 µg $256.00 Add to Cart
A52737-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody, Biotin Conjugated
CSNK1E Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56249-05050 µg $256.00 Add to Cart
A56249-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody, FITC Conjugated
CSNK1E Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56248-05050 µg $256.00 Add to Cart
A56248-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody, FITC Conjugated
CSNK1E Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52738-05050 µg $256.00 Add to Cart
A52738-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody, HRP Conjugated
CSNK1E Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52739-05050 µg $256.00 Add to Cart
A52739-100100 µg $359.00 Add to Cart
Antibodies
CSNK1E Polyclonal Antibody, HRP Conjugated
CSNK1E Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56247-05050 µg $256.00 Add to Cart
A56247-100100 µg $359.00 Add to Cart
Antibodies
CSNK2A1 Polyclonal Antibody
CSNK2A1 Polyclonal Antibody

Application: ELISA, IF, IHC, IP, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57361-02020 µg $99.00 Add to Cart
A57361-05050 µg $256.00 Add to Cart
A57361-100100 µg $359.00 Add to Cart
Antibodies
CSNK2A1 Polyclonal Antibody, Biotin Conjugated
CSNK2A1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57364-05050 µg $256.00 Add to Cart
A57364-100100 µg $359.00 Add to Cart
Antibodies
CSNK2A1 Polyclonal Antibody, FITC Conjugated
CSNK2A1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57363-05050 µg $256.00 Add to Cart
A57363-100100 µg $359.00 Add to Cart
Antibodies
CSNK2A1 Polyclonal Antibody, HRP Conjugated
CSNK2A1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57362-05050 µg $256.00 Add to Cart
A57362-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]  ... 6  7  8  9  10 ...  [Next >>]  Displaying 141 to 160 (of 998 products)
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