Serving Epigenetic Researchers Since 2005

All Your Epigenetic Lab Needs. In One Place.

Explore popular assays across DNA methylation, RNA modification, histone analysis, and chromatin research.

Trusted Assays Well-cited kits researchers return to most for core applications and publishable results.
Workflow Focused Pre-built bundle paths make it easier to move from an initial assay into the next experimental step.
Budget Friendly Purchase kits as a bundle to maximize your lab budget, or reach out to us for a quote.

Why Researchers Choose EpigenTek

Quality Guarantee The EpigenTek Guarantee policy ensures 100% working results as advertised. Otherwise we will replace it or refund it.

Speed & Simplicity Products are developed for easier workflows and shorter procedures, helping labs generate results faster without unnecessary complexity.

Convenience A broad catalog plus complementary bundle options makes it easier to source connected assays and reagents from one supplier.

Popular Epigenetic Assays by Workflows & Research Area

DNA methylation controls gene activity by adding chemical marks to DNA, most commonly at cytosine residues. It is one of the core epigenetic mechanisms behind development, cell identity, and disease-associated gene regulation.

Fast global 5-mC and 5-hmC screening Any-species DNA methylation analysis Easy path to RRBS and WGBS

MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit

Cat# P-1030

Quantify global 5-mC levels from purified DNA samples in a fast ELISA-style workflow.

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MethylFlash Global DNA Hydroxymethylation (5-hmC) ELISA Easy Kit

Cat# P-1032

Measure global 5-hmC levels to assess hydroxymethylation and active demethylation dynamics.

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Methylamp DNA Modification Kit

Cat# P-1001

Convert DNA for downstream methylated cytosine analysis in gene-specific bisulfite workflows.

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EpiQuik DNMT Activity / Inhibition ELISA Easy Kit

Cat# P-3139

Measure DNA methyltransferase activity or inhibition from nuclear extracts or purified enzymes.

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Epigenase 5mC-Hydroxylase TET Activity / Inhibition Assay Kit

Cat# P-3086

Assess TET enzyme activity or inhibition to study active DNA demethylation pathways.

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DNA Methylation Workflow Bundles

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Bundle - Global 5-mC DNA Methylation and MeDIP

Cat# B13015-1

Measure global DNA methylation first, then enrich methylated regions for locus-specific downstream analysis.

Workflow ELISA to qPCR/NGS

Kits included

MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit (96 reactions)Cat# P-1030-96
Methylamp Methylated DNA Capture (MeDIP) Kit (48 reactions)Cat# P-1015-48

~~$1,299~~ $1,104.15

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Bundle - Global 5-mC DNA Hydroxymethylation and hMeDIP

Cat# B13238-1

Start by quantifying global 5-hmC, then follow with hydroxymethylated DNA enrichment for more targeted analysis.

Workflow ELISA to qPCR/NGS

Kits included

MethylFlash Global DNA Hydroxymethylation (5-hmC) ELISA Easy Kit (96 reactions)Cat# P-1032-96
EpiQuik Hydroxymethylated DNA Immunoprecipitation (hMeDIP) Kit (96 reactions)Cat# P-1038-96

~~$1,968~~ $1,771.20

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Bundle - DNMT Activity/Inhibition

Cat# B33902-1

This bundle combines nuclear extraction with DNMT activity measurement so researchers can move directly into functional enzyme analysis.

Workflow Extraction to enzyme activity assay

Kits included

EpiQuik DNMT Activity / Inhibition ELISA Easy Kit (96 assays)Cat# P-3139-96
EpiQuik Nuclear Extraction Kit (100 extractions)Cat# OP-0002-100

~~$850~~ $765.00

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Bundle - TET Activity / Inhibition

Cat# B38602-1

For researchers focused on active demethylation pathways, this bundle pairs sample preparation with TET activity measurement.

Workflow Extraction to enzyme activity assay

Kits included

Epigenase 5mC-Hydroxylase TET Activity / Inhibition Assay Kit (96 assays)Cat# P-3086-96
EpiQuik Nuclear Extraction Kit (100 extractions)Cat# OP-0002-100

~~$886.00~~ $797.40

DNA Methylation Research Bundles

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Bundle - Global DNA 5-mC and 5-hmC Analysis

Cat# B13032-1

Measure both methylation and hydroxymethylation in the same study to distinguish stable methylation changes from active demethylation-related shifts.

Readout Dual ELISA panel

Kits included

MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit (96 reactions)Cat# P-1030-96
MethylFlash Global DNA Hydroxymethylation (5-hmC) ELISA Easy Kit (96 reactions)Cat# P-1032-96

~~$1,245~~ $1,058.25

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Bundle - DNMT and TET Enzymatic Regulation

Cat# B33986-1

Pair DNMT and TET activity assays to evaluate both methylation establishment and active demethylation regulation in the same study.

Readout Dual enzyme activity panel

Kits included

EpiQuik DNMT Activity / Inhibition ELISA Easy Kit (96 assays)Cat# P-3139-96
Epigenase 5mC-Hydroxylase TET Activity / Inhibition Assay Kit (96 assays)Cat# P-3086-96

~~$1,338~~ $1,204.20

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Bundle - Global DNA 5-mC and DNMT Activity Regulation

Cat# B13039-1

Combine a global methylation readout with DNMT activity to assess whether methylation changes may be associated with altered methyltransferase function.

Readout ELISA plus enzyme activity assay

Kits included

MethylFlash Global DNA Methylation DNA (5-mC) ELISA Easy Kit (96 reactions)Cat# P-1030-96
EpiQuik DNMT Activity / Inhibition ELISA Easy Kit (96 assays)Cat# P-3139-96

~~$1,263~~ $1,073.55

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Bundle - Global DNA 5-hmC Level and TET Activity Regulation

Cat# B13286-1

Pair a global hydroxymethylation measurement with a related enzyme activity assay for stronger biological interpretation.

Readout ELISA plus enzyme activity assay

Kits included

MethylFlash Global DNA Hydroxymethylation (5-hmC) ELISA Easy Kit (96 reactions)Cat# P-1032-96
Epigenase 5mC-Hydroxylase TET Activity / Inhibition Assay Kit (96 assays)Cat# P-3086-96

~~$1,320~~ $1,188.00

RNA modification adds regulatory marks to RNA after transcription and helps control splicing, stability, localization, and translation. It is a fast-growing area of epigenetics because these reversible marks influence how gene expression is executed at the RNA level.

Fast entry into epitranscriptomics Works across mRNA and non-coding RNA From screening to enrichment, seq, and enzyme assays

EpiQuik m6A RNA Methylation Quantification Kit

Cat# P-9005

Quantify global m6A RNA methylation levels from total RNA in a simple colorimetric assay.

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EpiQuik CUT&RUN m6A RNA Enrichment (MeRIP) Kit

Cat# P-9018

Enrich m6A-modified RNA fragments for downstream qPCR or sequencing-based transcript profiling.

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EpiNext CUT&LUNCH RNA Immunoprecipitation (RIP) Kit

Cat# P-2037

Capture protein-bound RNA complexes from intact cells for RIP-qPCR or RIP-seq analysis.

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Epigenase m6A Methylase Activity / Inhibition Assay Kit

Cat# P-9019

Measure RNA methyltransferase activity or inhibition for m6A writer enzyme studies.

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Epigenase m6A Demethylase Activity / Inhibition Assay Kit

Cat# P-9013

Assess RNA demethylase activity or inhibition to study m6A eraser regulation.

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RNA Modification Workflow Bundles

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Bundle - Global RNA m6A Methylation Analysis

Cat# B90518-1

Screen global m6A first, then move into enrichment-based analysis of modified transcripts.

Workflow ELISA to qPCR/NGS

Kits included

EpiQuik m6A RNA Methylation Quantification Kit (96 reactions) Cat# P-9005-96
EpiQuik CUT&RUN m6A RNA Enrichment (MeRIP) Kit (24 reactions)Cat# P-9018-24

~~$1,047~~ $942.30

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Bundle - m6A RNA Sequencing Multiplexing

Cat# B91660-1

Push directly into m6A sequencing with a more efficient multiplexed workflow for handling multiple samples.

Workflow Sequencing-ready NGS workflow

Kits included

EpiNext CUT&RUN RNA m6A-Seq Kit (24 reactions)Cat# P-9016-24
EpiNext NGS Barcode Index Set (24 barcodes / 288 reactions)Cat# P-1060-288

~~$1,442~~ $1,297.80

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Bundle - m6A Demethylase Activity / Inhibition

Cat# B91302-1

Go from nuclear extract preparation into functional demethylase activity analysis with a matched set of products.

Workflow Extraction to enzyme activity assay

Kits included

Epigenase m6A Demethylase Activity / Inhibition Assay Kit (96 assays) Cat# P-9013-96
EpiQuik Nuclear Extraction Kit (100 extractions)Cat# OP-0002-100

~~$864~~ $777.60

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Bundle - m6A Methylase Activity / Inhibition

Cat# B91902-1

Support m6A writer-focused studies by combining extraction and activity measurement into one cleaner workflow choice.

Workflow Extraction to enzyme activity assay

Kits included

Epigenase m6A Methylase Activity / Inhibition Assay Kit (96 assays)Cat# P-9019-96
EpiQuik Nuclear Extraction Kit (100 extractions)Cat# OP-0002-100

~~$850~~ $765.00

RNA Modification Research Bundles

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Bundle - Global RNA m6A and 5-mC Analysis

Cat# B90509-1

Measure two important RNA methylation marks in one study design for broader epitranscriptomic insight.

Readout Dual RNA methylation panel

Kits included

EpiQuik m6A RNA Methylation Quantification Kit (96 reactions)Cat# P-9005-96
MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric) (96 reactions)Cat# P-9009-96

~~$1,180~~ $1,062.00

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Bundle - m6A RNA Enzymatic Regulation

Cat# B91913-1

Pair m6A writer and eraser activity assays to compare both sides of RNA methylation regulation.

Readout Dual enzyme activity panel

Kits included

Epigenase m6A Methylase Activity / Inhibition Assay Kit (96 assays)Cat# P-9019-96
Epigenase m6A Demethylase Activity / Inhibition Assay Kit (96 assays)Cat# P-9013-96

~~$1,316~~ $1,184.40

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Bundle - m6A RNA Methylation and Demethylase Regulation

Cat# B90513-1

Connect an overall m6A methylation measurement with demethylase activity for more interpretive context.

Readout ELISA plus enzyme activity assay

Kits included

EpiQuik m6A RNA Methylation Quantification Kit (96 reactions)Cat# P-9005-96
Epigenase m6A Demethylase Activity / Inhibition Assay Kit (96 assays)Cat# P-9013-96

~~$1,246~~ $1,121.40

Histone modifications are chemical marks on histone proteins that help determine how tightly DNA is packaged and how accessible genes are. They are central to epigenetics because they shape chromatin state, transcriptional activity, and broader gene regulation programs.

Specific H3/H4 histone mark coverage in one run No expensive instrumentation required Connect PTM patterns to HDAC/HAT and demethylase activity

EpiQuik Histone H3 Modification Multiplex Assay Kit

Cat# P-3100

Profile 21 key histone H3 modification patterns in one multiplex colorimetric assay.

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EpiQuik Histone H4 Modification Multiplex Assay Kit

Cat# P-3102

Simultaneously detect 10 major histone H4 modification patterns for broader PTM screening.

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Epigenase HDAC Activity / Inhibition Direct Assay Kit

Cat# P-4034

Measure HDAC activity or inhibition for histone deacetylation pathway studies.

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EpiQuik HAT Activity / Inhibition Assay Kit

Cat# P-4003

Assess histone acetyltransferase activity or inhibition in chromatin acetylation studies.

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Epigenase LSD1 Demethylase Activity / Inhibition Assay Kit

Cat# P-3078

Quantify LSD1 demethylase activity or inhibition for H3K4 and H3K9 regulation studies.

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Histone Modification Workflow Bundles

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Bundle - Histone H3 Modification Screening

Cat# B30006-1

Pair histone extraction with H3 multiplex analysis so researchers can move directly into PTM screening.

Workflow Extraction to multiplex assay

Kits included

EpiQuik Total Histone Extraction Kit (100 extractions)Cat# OP-0006-100
EpiQuik Histone H3 Modification Multiplex Assay Kit (96 reactions) Cat# P-3100-96

~~$965~~ $868.50

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Bundle - Histone H4 Modification Screening

Cat# B30206-1

Pair extraction with H4 multiplex analysis for a cleaner, faster route into H4-focused work.

Workflow Extraction to multiplex assay

Kits included

EpiQuik Total Histone Extraction Kit (100 extractions)Cat# OP-0006-100
EpiQuik Histone H4 Modification Multiplex Assay Kit (96 reactions)Cat# P-3102-96

~~$852~~ $766.80

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Bundle - HDAC Activity / Inhibition

Cat# B43402-1

Move from nuclear extraction into HDAC activity measurement without separately assembling the workflow.

Workflow Extraction to enzyme activity assay

Kits included

EpiQuik Nuclear Extraction Kit (100 extractions)Cat# OP-0002-100
Epigenase HDAC Activity / Inhibition Direct Assay Kit (96 assays)Cat# P-4034-96

~~$657~~ $591.30

Histone Modification Research Bundles

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Bundle - Histone H3 and H4 Post-Translational Modification (PTM) Profiling

Cat# B30002-1

Profile both H3 and H4 modifications together for a broader view of chromatin state.

Readout Dual multiplex PTM panel

Kits included

EpiQuik Histone H3 Modification Multiplex Assay Kit (96 reactions) Cat# P-3100-96
EpiQuik Histone H4 Modification Multiplex Assay Kit (96 reactions) Cat# P-3102-96

~~$1,523~~ $1,370.70

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Bundle - H3K4 Methylation Regulation

Cat# B30278-1

Combine methyltransferase and demethylase perspectives around H3K4 for more complete interpretation.

Readout Dual enzyme regulation panel

Kits included

EpiQuik Histone Methyltransferase Activity / Inhibition Assay Kit (H3-K4) (96 assays) Cat# P-3027-96
Epigenase LSD1 Demethylase Activity / Inhibition Assay Kit (96 assays) Cat# P-3078-96

~~$1,397~~ $1,257.30

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Bundle - Histone Acetylation Regulation

Cat# B40334-1

Measure both HAT and HDAC activity together to study the balance of acetylation control.

Readout Dual enzyme activity panel

Kits included

EpiQuik HAT Activity / Inhibition Assay Kit (96 assays) Cat# P-4003-96
Epigenase HDAC Activity / Inhibition Direct Assay Kit (96 assays) Cat# P-4034-96

~~$928~~ $835.20

Chromatin studies examine how DNA is packaged with proteins and how that packaging influences accessibility, interaction, and transcriptional control. Chromatin structure determines whether regulatory regions are open, occupied, or silenced.

Ultra low-input starting materials Fast intact-cell chromatin workflows High enrichment for accurate NGS