UBE2D1 Polyclonal Antibody

Please see "Related Products" for an equivalent antibody.

Background
UBE2D1 (ubiquitin-conjugating enzyme E2D 1) is a protein coding gene. Proteins modified with ubiquitin are able to target abnormal or short-lived proteins for degradation. Ubiquitination uses three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). UBE2D1 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is similar to a stimulator of iron transport (SFT), and is also up-regulated in hereditary hemochromatosis. UBE2D1 functions in the ubiquitination of protein p53, a tumor-suppressor protein, and HIF1alpha by interacting with E1 and E3. Two transcript variants encoding different isoforms have been found for this gene.

Description
UBE2D1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
P51668

Purification
Affinity Purified

Immunogen
Recombinant Protein of Human UBE2D1

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
SFT, UBCH5, UBC4/5, UBCH5A, E2(17)KB1

Application
WB, IHC; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200