Holiday Winter Sale Holiday Winter Sale: Use code E1812WTR to save 15% on your entire order. Ends 12/28/18. » Learn More
Epigentek Home
 
EpiGentek Guarantee
Refine Your Results
Introduction to Epigenetics
Signal Transduction Antibodies

Signal Transduction Antibodies

Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intracellularly. A wide range of antibodies are involved in signal transduction, such as cell surface receptor and kinase antibodies, intracellular kinase and adaptor protein antibodies, phosphatase antibodies, and secreted growth factor antibodies. Signaling pathways and their fluid dynamic processes can be studied by researchers aiming to learn more about their far-reaching morphological effects and especially their influence on the regulation of gene expression. Signal transduction antibodies can also offer insight into various pathways and their role in the development of diseases, for example, Alzheimer’s, lupus, cancer and rheumatoid arthritis.
Cell Surface Receptor & Kinase Antibodies
Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Intracellular Kinase & Adaptor Protein Antibodies
After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

Phosphatase Antibodies
Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Secreted Growth Factor Antibodies
Growth factors, peptide hormones, neurotransmitters and other secreted molecules initiate diverse signals involved in controlling cellular growth and proliferation, tissue development and differentiation, cellular metabolism and other biological processes. They initiate signals by binding to a receptor on the cell surface, which then undergoes a conformational change leading to an intracellular signaling cascade.

Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 41 to 60 (of 2525 products)
AGRP Polyclonal Antibody
AGRP Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A56699-05050 µg $256.00 Add to Cart
A56699-100100 µg $359.00 Add to Cart
Antibodies
AGRP Polyclonal Antibody, Biotin Conjugated
AGRP Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A56702-05050 µg $256.00 Add to Cart
A56702-100100 µg $359.00 Add to Cart
Antibodies
AGRP Polyclonal Antibody, FITC Conjugated
AGRP Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A56701-05050 µg $256.00 Add to Cart
A56701-100100 µg $359.00 Add to Cart
Antibodies
AGRP Polyclonal Antibody, HRP Conjugated
AGRP Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A56700-05050 µg $256.00 Add to Cart
A56700-100100 µg $359.00 Add to Cart
Antibodies
AGT Polyclonal Antibody
AGT Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A50656-02020 µg $59.00 Add to Cart
A50656-05050 µg $256.00 Add to Cart
A50656-100100 µg $359.00 Add to Cart
Antibodies
AGT Polyclonal Antibody, Biotin Conjugated
AGT Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50659-05050 µg $256.00 Add to Cart
A50659-100100 µg $359.00 Add to Cart
Antibodies
AGT Polyclonal Antibody, FITC Conjugated
AGT Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50658-05050 µg $256.00 Add to Cart
A50658-100100 µg $359.00 Add to Cart
Antibodies
AGT Polyclonal Antibody, HRP Conjugated
AGT Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50657-05050 µg $256.00 Add to Cart
A50657-100100 µg $359.00 Add to Cart
Antibodies
AHNAK Polyclonal Antibody
AHNAK Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A68819-02020 µg $59.00 Add to Cart
A68819-05050 µg $249.00 Add to Cart
A68819-100100 µg $399.00 Add to Cart
Antibodies
AHNAK Polyclonal Antibody, Biotin Conjugated
AHNAK Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68822-05050 µg $249.00 Add to Cart
A68822-100100 µg $399.00 Add to Cart
Antibodies
AHNAK Polyclonal Antibody, FITC Conjugated
AHNAK Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68821-05050 µg $249.00 Add to Cart
A68821-100100 µg $399.00 Add to Cart
Antibodies
AHNAK Polyclonal Antibody, HRP Conjugated
AHNAK Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68820-05050 µg $249.00 Add to Cart
A68820-100100 µg $399.00 Add to Cart
Antibodies
AHNAK2 Polyclonal Antibody
AHNAK2 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A70007-02020 µg $59.00 Add to Cart
A70007-05050 µg $249.00 Add to Cart
A70007-100100 µg $399.00 Add to Cart
Antibodies
AHNAK2 Polyclonal Antibody, Biotin Conjugated
AHNAK2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70010-05050 µg $249.00 Add to Cart
A70010-100100 µg $399.00 Add to Cart
Antibodies
AHNAK2 Polyclonal Antibody, FITC Conjugated
AHNAK2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70009-05050 µg $249.00 Add to Cart
A70009-100100 µg $399.00 Add to Cart
Antibodies
AHNAK2 Polyclonal Antibody, HRP Conjugated
AHNAK2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70008-05050 µg $249.00 Add to Cart
A70008-100100 µg $399.00 Add to Cart
Antibodies
AKT1 Polyclonal Antibody
AKT1 Polyclonal Antibody

Application: ELISA, IF, IHC, IP, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A68300-02020 µg $59.00 Add to Cart
A68300-05050 µg $256.00 Add to Cart
A68300-100100 µg $359.00 Add to Cart
Antibodies
AKT1 Polyclonal Antibody, Biotin Conjugated
AKT1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53358-05050 µg $256.00 Add to Cart
A53358-100100 µg $359.00 Add to Cart
Antibodies
AKT1 Polyclonal Antibody, FITC Conjugated
AKT1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53359-05050 µg $256.00 Add to Cart
A53359-100100 µg $359.00 Add to Cart
Antibodies
AKT1 Polyclonal Antibody, HRP Conjugated
AKT1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53360-05050 µg $256.00 Add to Cart
A53360-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 41 to 60 (of 2525 products)
Epigentek is an epigenetics company that specializes in epigenetic kits, antibodies, reagents, and services for epigenetic research in DNA methylation, histone modification, and chromatin studies. Terms & Conditions | Privacy Policy | Site Map
Copyright © 2018 Epigentek Group Inc. All rights reserved.