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Introduction to Epigenetics
Signal Transduction Antibodies

Signal Transduction Antibodies

Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intracellularly. A wide range of antibodies are involved in signal transduction, such as cell surface receptor and kinase antibodies, intracellular kinase and adaptor protein antibodies, phosphatase antibodies, and secreted growth factor antibodies. Signaling pathways and their fluid dynamic processes can be studied by researchers aiming to learn more about their far-reaching morphological effects and especially their influence on the regulation of gene expression. Signal transduction antibodies can also offer insight into various pathways and their role in the development of diseases, for example, Alzheimer’s, lupus, cancer and rheumatoid arthritis.
Cell Surface Receptor & Kinase Antibodies
Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Intracellular Kinase & Adaptor Protein Antibodies
After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

Phosphatase Antibodies
Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Secreted Growth Factor Antibodies
Growth factors, peptide hormones, neurotransmitters and other secreted molecules initiate diverse signals involved in controlling cellular growth and proliferation, tissue development and differentiation, cellular metabolism and other biological processes. They initiate signals by binding to a receptor on the cell surface, which then undergoes a conformational change leading to an intracellular signaling cascade.

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ADGRL4 Polyclonal Antibody
ADGRL4 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58026-02020 µg $59.00 Add to Cart
A58026-05050 µg $256.00 Add to Cart
A58026-100100 µg $359.00 Add to Cart
Antibodies
ADGRL4 Polyclonal Antibody, Biotin Conjugated
ADGRL4 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58027-05050 µg $256.00 Add to Cart
A58027-100100 µg $359.00 Add to Cart
Antibodies
ADGRL4 Polyclonal Antibody, FITC Conjugated
ADGRL4 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58028-05050 µg $256.00 Add to Cart
A58028-100100 µg $359.00 Add to Cart
Antibodies
ADGRL4 Polyclonal Antibody, HRP Conjugated
ADGRL4 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58029-05050 µg $256.00 Add to Cart
A58029-100100 µg $359.00 Add to Cart
Antibodies
ADM Polyclonal Antibody
ADM Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Growth, Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A55846-02020 µg $59.00 Add to Cart
A55846-05050 µg $256.00 Add to Cart
A55846-100100 µg $359.00 Add to Cart
Antibodies
ADM Polyclonal Antibody, Biotin Conjugated
ADM Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Growth, Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55849-05050 µg $256.00 Add to Cart
A55849-100100 µg $359.00 Add to Cart
Antibodies
ADM Polyclonal Antibody, FITC Conjugated
ADM Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Growth, Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55848-05050 µg $256.00 Add to Cart
A55848-100100 µg $359.00 Add to Cart
Antibodies
ADM Polyclonal Antibody, HRP Conjugated
ADM Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Growth, Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55847-05050 µg $256.00 Add to Cart
A55847-100100 µg $359.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody
ADORA1 Polyclonal Antibody

Application: ELISA, IF
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A62058-02020 µg $59.00 Add to Cart
A62058-05050 µg $256.00 Add to Cart
A62058-100100 µg $359.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody, Biotin Conjugated
ADORA1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62061-05050 µg $256.00 Add to Cart
A62061-100100 µg $359.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody, FITC Conjugated
ADORA1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62060-05050 µg $256.00 Add to Cart
A62060-100100 µg $359.00 Add to Cart
Antibodies
ADORA1 Polyclonal Antibody, HRP Conjugated
ADORA1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62059-05050 µg $256.00 Add to Cart
A62059-100100 µg $359.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody
Adrb2 Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
Trial Size Available: Yes
A57241-02020 µg $59.00 Add to Cart
A57241-05050 µg $256.00 Add to Cart
A57241-100100 µg $359.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody, Biotin Conjugated
Adrb2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A57244-05050 µg $256.00 Add to Cart
A57244-100100 µg $359.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody, FITC Conjugated
Adrb2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A57243-05050 µg $256.00 Add to Cart
A57243-100100 µg $359.00 Add to Cart
Antibodies
Adrb2 Polyclonal Antibody, HRP Conjugated
Adrb2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Rat
A57242-05050 µg $256.00 Add to Cart
A57242-100100 µg $359.00 Add to Cart
Antibodies
ADRBK1 Polyclonal Antibody
ADRBK1 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A53488-02020 µg $59.00 Add to Cart
A53488-05050 µg $256.00 Add to Cart
A53488-100100 µg $359.00 Add to Cart
Antibodies
ADRBK1 Polyclonal Antibody, Biotin Conjugated
ADRBK1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53485-05050 µg $256.00 Add to Cart
A53485-100100 µg $359.00 Add to Cart
Antibodies
ADRBK1 Polyclonal Antibody, FITC Conjugated
ADRBK1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53486-05050 µg $256.00 Add to Cart
A53486-100100 µg $359.00 Add to Cart
Antibodies
ADRBK1 Polyclonal Antibody, HRP Conjugated
ADRBK1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53487-05050 µg $256.00 Add to Cart
A53487-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 21 to 40 (of 2525 products)
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