BackgroundThe protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration.
DescriptionADM Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityMouse
IsotypeIgG
Uniprot IDP35318
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 50-150 of human ADM (NP_001115.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesADM; AM; PAMP
ApplicationWB; Recommended dilution: WB: 1:500-1:2000