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OGG1 Polyclonal Antibody

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Western blot analysis of extracts of human heart tissue, using OGG1 Polyclonal Antibody.
Immunohistochemistry of paraffin-embedded mouse brain using OGG1 Polyclonal Antibody at dilution of 1:200 (400x lens).
Application: IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-6703-05050 µlView
A-6703-100100 µlView
Product Overview

Background
8-Oxoguanine glycosylase (OGG1) is an enzyme responsible for the removal of 8-oxoguanine (8-oxoG), a mutagenic base byproduct that emerges as a result of reactive oxygen species (ROS) exposure. The action of OGG1 involves lyase activity for chain cleavage. Two major groups of alternative splice variants exist for this gene. Type 1 variants end with exon 7 and type 2 variants end with exon 8. The N-terminal region for all variants is the same. This region contains a mitochondrial targeting signal that is necessary for mitochondrial localization. Several alternative splice variants for OGG1 have been identified, yet the nature of every variant is not fully understood.

Description
OGG1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
O15527

Purification
Affinity Purified

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
HMMH, MUTM, OGH1, HOGG1

Application
WB, IHC; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200

User Guide & MSDS

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