BackgroundThis gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
DescriptionMTCH2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDQ9Y6C9
PurificationAffinity Purified
ImmunogenRecombinant protein of human MTCH2.
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesMTCH2; HSPC032; MIMP; SLC25A50
ApplicationWB, IHC, IF; Recommended dilution: WB 1:1000 - 1:3000, IHC 1:50 - 1:200, IF 1:50 - 1:200