Histone deacetylases (HDACs) play a critical role in transcriptional repression of gene expression in eukaryotic cells through catalyzing the hydrolytic removal of acetyl groups from histone lysine residues. Three distinct families of HDACs have been described, comprising a group of at least 20 proteins in humans. HDAC4 is a class I histone deacetylase.
Mouse monoclonal antibody raised against a partial recombinant HDAC4, clone 2B11.
Protein A purified
HDAC4 (NP_006028, 551 a.a. ~ 648 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
In 1x PBS, pH 7.2
Aliquot and store at -20ºC or lower. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
For maximum recovery of the products, centrifuge the vial prior to opening the cap.
AHO3 antibody, BDMR antibody, EC 188.8.131.52 antibody, HA6116 antibody, HD 4 antibody, HDACA antibody, Histone Deacetylase 4 antibody, Histone Deacetylase A antibody, KIAA0288 antibody
Applications & Suggested Dilutions*
Western Blot: 0.5-1 µg/ml
ELISA: 0.25-1 µg/ml
Immunohistochemistry (IHC): 2.5 µg/ml
*The end user is responsible for determining optimal working dilutions.
Western Blot detection against Immunogen (36.89 KDa).
Note: This item was formerly catalog no. ABB-4004 (ABB4004)